Review Article|Articles in Press

The Role of Point-of-Care Testing in Specific Populations

Published:March 15, 2023DOI:


      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.


      Subscribe to Clinics in Laboratory Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Kost G.
        Principles and practice of point-of-care testing. Lippincott Williams & Wilkins, Philadelphia, PA2002: 654
        • Parvin C.A.
        • Lo S.F.
        • Deuser S.M.
        • et al.
        Impact of point-of-care testing on patients’ length of stay in a large emergency department.
        Clin Chem. 1996; 42: 711-717
        • Lilly C.M.
        • Ensom E.
        • Teebagy S.
        • et al.
        Patient preferences for point-of-care testing: survey validation and results.
        Point Care. 2020; 19: 112-115
        • Geffner M.E.
        • Kaplan S.A.
        • Lippe B.M.
        • et al.
        Self-monitoring of blood glucose levels and intensified insulin therapy: acceptability and efficacy in childhood diabetes.
        JAMA. 1983; 249: 2913-2916
        • Peaper D.R.
        • Durant T.
        • Campbell S.
        Distributed microbiology testing: Bringing infectious disease diagnostics to point of care.
        Clin Lab Med. 2019; 39: 419-431
        • Centers for Disease Control and Prevention
        HIV surveillance report: estimated HIV incidence and prevalence in the United States, 2015-2019.
        (Available at:) (Accessed October 30, 2022)
        • Li Z.
        • Purcell D.W.
        • Sansom S.L.
        • et al.
        Vital signs: HIV transmission along the continuum of care—United States, 2016.
        MMWR Morb Mortal Wkly Rep. 2019; 68: 267-272
      1. Centers for Disease Control. Ending the HIV epidemic: a plan for America. Available at: ending the HIV epidemic: a plan for America ( Available at: Accessed October 31, 2022.

        • Branson B.M.
        • Handsfield H.H.
        • Lampe M.A.
        • et al.
        Revised recommendations for HIV testing of adults, adolescents, and pregnant women in health-care settings.
        MMWR Recomm Rep (Morb Mortal Wkly Rep). 2006; 55 (No. RR-14). Available at:)
        • DiNenno E.A.
        • Prejean J.
        • Irwin K.
        • et al.
        Recommendations for HIV screening of gay, bisexual, and other men who have sex with men—United States, 2017.
        MMWR Morb Mortal Wkly Rep. 2017; 66: 830-832
        • Hecht J.
        • Sanchez T.
        • Sullivan P.S.
        • et al.
        Increasing access to HIV testing through direct-to-consumer HIV self-test distribution—United States, March 31, 2020-March 30, 2021.
        Morb Mortal Wkly Rep. 2021; 70: 1322-1325
        • Katz D.A.
        • Golden M.R.
        • Hughes J.P.
        • et al.
        HIV self-testing increases HIV testing frequency in high risk men who have sex with men: a randomized controlled trial.
        J Acquir Immune Defic Syndr. 2018; 78: 505-512
        • US Food and Drug Administration
        FDA approves first over-the-counter home-use rapid HIV test.
        FDA news release, 2012 (Available at:) (Accessed October 31, 2022)
        • Steehler K.
        • Siegler A.J.
        Bringing HIV self-testing to scale in the United States: a review of challenges, potential solutions, and future opportunities.
        J Clin Microbiol. 2019; 57: 1-12
        • Pai N.P.
        • Vadnais C.
        • Denkinger C.
        • et al.
        Point-of-care testing for infectious diseases: diversity, complexity, and barriers in low- and middle-income countries.
        PLoS Med. 2012; 9: e1001306
        • Herd G.C.
        • Musaad S.M.
        Point-of-care testing in rural and remote settings to improve access and improve outcomes: a snapshot of the New Zealand experience.
        Arch Pathol Lab Med. 2021; 145: 327-335
        • Valencia J.
        • Lazarus J.V.
        • Ceballos F.C.
        • et al.
        Differences in the hepatitis C virus cascade of care and time to initiation of therapy among vulnerable subpopulations using a mobile unit as point-of-care.
        Liver Int. 2022; 42: 309-319
        • Makhudu S.J.
        • Kuupiel D.
        • Gwala N.
        • et al.
        The use of patient self-testing in low- and middle-income countries: a systematic scoping review.
        Point Care. 2019; 18: 9-16
        • Bond C.S.
        • Hewitt-Taylor J.
        How people with diabetes integrate self-monitoring of blood glucose into their self-management strategies.
        Inform Prim Care. 2014; 21: 64-69
        • Heneghan C.J.
        • Garcia-Alamino J.M.
        • Spencer E.A.
        • et al.
        Self-monitoring and self-management of oral anticoagulation.
        Cochrane Database Syst Rev. 2016; 7: CD003839
        • Madimenos F.C.
        • Gildner T.E.
        • Eick G.N.
        • et al.
        Bringing the lab bench to the field: point-of-care testing for enhancing health research and stakeholder engagement in rural/remote, indigenous, and resource-limited contexts.
        Am J Hum Biol. 2022; 34: e23808
        • Kettler H.
        • White K.
        • Hawkes S.
        Mapping the landscape of diagnostics for sexually transmitted infections.
        WHO/TDR, Geneva2004
        • Pai M.
        • Ghiasi M.
        • Pai N.P.
        Point-of-care diagnostic testing in global health: what is the point?.
        Microbe. 2015; 10: 103-107
        • Kost G.
        Geospatial science and point-of-care testing: creating solutions for population access, emergencies, outbreaks, and disasters.
        Front Public Health. 2019; 7: 329
        • Lau M.S.Y.
        • Gibson G.J.
        • Adrakey H.
        • et al.
        A mechanistic spatio-temporal framework for modeling individual-to-individual transmission-With an application to the 2014-2015 West Africa Ebola outbreak.
        PLoS Comput Biol. 2017; 13: e1005798