Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.
Content published before 2002 is available via pay-per-view purchase only.
Subscribe:
Subscribe to Clinics in Laboratory MedicineAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Nivolumab plus ipilimumab in advanced non-small-cell lung cancer.N Engl J Med. 2019; 381: 2020-2031
- Nivolumab plus ipilimumab in lung cancer with a high tumor mutational burden.N Engl J Med. 2018; 378: 2093-2104
- Genetic basis for clinical response to CTLA-4 blockade in melanoma.N Engl J Med. 2014; 371: 2189-2199
- Tumor mutational load predicts survival after immunotherapy across multiple cancer types.Nat Genet. 2019; 51: 202-206
- Transcriptional profiling and genotyping of degraded nucleic acids from autopsy tissue samples after prolonged formalin fixation times.Int J Clin Exp Pathol. 2011; 4: 156-161
- Sequence artifacts in DNA from formalin-fixed tissues: causes and strategies for minimization.Clin Chem. 2015; 61: 64-71
- Conversions of formaldehyde-modified 2'-deoxyadenosine 5'-monophosphate in conditions modeling formalin-fixed tissue dehydration.J Histochem Cytochem. 2006; 54: 301-310
- Tissue extraction of DNA and RNA and analysis by the polymerase chain reaction.J Clin Pathol. 1990; 43: 499-504
- Instability and decay of the primary structure of DNA.Nature. 1993; 362: 709-715
- Clinical whole-genome sequencing from routine formalin-fixed, paraffin-embedded specimens: pilot study for the 100,000 Genomes Project.Genet Med. 2018; 20: 1196-1205
- Use of uracil-DNA glycosylase enzyme to reduce DNA-related artifacts from formalin-fixed and paraffin-embedded tissues in diagnostic routine.Appl Cancer Res. 2019; 39: 7
- Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.PLoS One. 2018; 13: e0196434
- Base-excision repair of oxidative DNA damage.Nature. 2007; 447: 941-950
- Targeted next generation sequencing as a reliable diagnostic assay for the detection of somatic mutations in tumours using minimal DNA amounts from formalin fixed paraffin embedded material.PLoS One. 2016; 11: e0149405
- Genomic profiling of gynecologic cancers and implications for clinical practice.Curr Opin Obstet Gynecol. 2017; 29: 18-25
- Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.Nat Med. 2017; 23: 703-713
- Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing.Nat Biotechnol. 2013; 31: 1023-1031
- Validation of the Oncomine focus panel for next-generation sequencing of clinical tumour samples.Virchows Arch. 2018; 473: 489-503
- Detection of novel germline mutations for breast cancer in non-BRCA1/2 families.FEBS J. 2015; 282: 3424-3437
- Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.Nature. 2005; 434: 917-921
- Institutional implementation of clinical tumor profiling on an unselected cancer population.JCI Insight. 2016; 1: e87062
- Pan-cancer whole-genome analyses of metastatic solid tumours.Nature. 2019; 575: 210-216
- Whole genome sequencing as a diagnostic test: challenges and opportunities.Clin Chem. 2014; 60: 724-733
- Low-pass whole-genome sequencing of circulating cell-free DNA demonstrates dynamic changes in genomic copy number in a squamous lung cancer clinical cohort.Clin Cancer Res. 2019; 25: 2254-2263
- Comparison of circulating tumour DNA and extracellular vesicle DNA by low-pass whole-genome sequencing reveals molecular drivers of disease in a breast cancer patient.Biomedicines. 2020; 9: 14
- EGFR amplification and outcome in a randomised phase III trial of chemotherapy alone or chemotherapy plus panitumumab for advanced gastro-oesophageal cancers.Gut. 2021; 70: 1632-1641
- Evaluation of hybridization capture versus amplicon-based methods for whole-exome sequencing.Hum Mutat. 2015; 36: 903-914
- Next-generation sequencing platforms.Annu Rev Anal Chem (Palo Alto Calif). 2013; 6: 287-303
- Clinical validation of a next-generation sequencing genomic Oncology panel via cross-platform benchmarking against established amplicon sequencing assays.J Mol Diagn. 2017; 19: 43-56
- Application of long-read sequencing to the detection of structural variants in human cancer genomes.Comput Struct Biotechnol J. 2021; 19: 4207-4216
- Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing.Cell Rep. 2021; 37: 110022
- Isoform age - splice isoform profiling using long-read technologies.Front Mol Biosci. 2021; 8: 711733
- Changing technologies of RNA sequencing and Their applications in clinical Oncology.Front Oncol. 2020; 10: 447
- Non-coding RNA networks in cancer.Nat Rev Cancer. 2018; 18: 5-18
- Large non-coding RNAs: missing links in cancer?.Hum Mol Genet. 2010; 19: R152-R161
- Comparison of RNA-based next-generation sequencing assays for the detection of NTRK gene fusions.J Mol Diagn. 2021; 23: 1443-1451
- DNA-based versus RNA-based detection of MET exon 14 skipping events in lung cancer.J Thorac Oncol. 2019; 14: 737-741
- Using breast cancer gene expression signatures in clinical practice: unsolved issues, ongoing trials and future perspectives.Cancers (Basel). 2021; 13: 4840
- The Prosigna 50-gene profile and responsiveness to adjuvant anthracycline-based chemotherapy in high-risk breast cancer patients.NPJ Breast Cancer. 2020; 6: 7
- Molecular classification and treatment of diffuse large B-cell lymphoma and primary Mediastinal B-cell lymphoma.Cancer J. 2020; 26: 195-205
- Advances in the molecular classification of pediatric brain tumors: a guide to the galaxy.J Pathol. 2020; 251: 249-261
- Review of molecular classification and treatment implications of pediatric brain tumors.Curr Opin Pediatr. 2018; 30: 3-9
- Single-cell RNA sequencing and bioinformatics as tools to decipher cancer heterogenicity and mechanisms of drug resistance.Biochem Pharmacol. 2021; 195: 114811
- mRNA-Seq whole-transcriptome analysis of a single cell.Nat Methods. 2009; 6: 377-382
- Tutorial: guidelines for the computational analysis of single-cell RNA sequencing data.Nat Protoc. 2021; 16: 1-9
- Signatures of mutational processes in human cancer.Nature. 2013; 500: 415-421
- Factors that influence the mutagenic patterns of DNA adducts from chemical carcinogens.Mutat Res. 2000; 463: 215-246
- Microsatellite instability detection using a large next-generation sequencing cancer panel across diverse tumour types.J Clin Pathol. 2020; 73: 83-89
- Detection of microsatellite instability biomarkers via next-generation sequencing.Methods Mol Biol. 2020; 2055: 119-132
- Classification and characterization of microsatellite instability across 18 cancer types.Nat Med. 2016; 22: 1342-1350
- Immune checkpoint inhibitors for the treatment of MSI-H/MMR-D colorectal cancer and a perspective on resistance mechanisms.Br J Cancer. 2019; 121: 809-818
- Pembrolizumab in microsatellite-instability-high advanced colorectal cancer.N Engl J Med. 2020; 383: 2207-2218
- Genomic features of response to combination immunotherapy in patients with advanced non-small-cell lung cancer.Cancer Cell. 2018; 33: 843-852.e4
- Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.Science. 2015; 350: 207-211
- Homologous recombination deficiency: exploiting the fundamental vulnerability of ovarian cancer.Cancer Discov. 2015; 5: 1137-1154
- Germline and somatic mutations in homologous recombination genes predict platinum response and survival in ovarian, fallopian tube, and peritoneal carcinomas.Clin Cancer Res. 2014; 20: 764-775
- Aligning tumor mutational burden (TMB) quantification across diagnostic platforms: phase II of the Friends of Cancer Research TMB Harmonization Project.Ann Oncol. 2021; 32: 1626-1636
- Harmonization and standardization of panel-based tumor mutational burden measurement: real-world results and recommendations of the quality in pathology study.J Thorac Oncol. 2020; 15: 1177-1189
- Size matters: dissecting key parameters for panel-based tumor mutational burden analysis.Int J Cancer. 2019; 144: 848-858
- The landscape of actionable genomic alterations in cell-free circulating tumor DNA from 21,807 advanced cancer patients.Clin Cancer Res. 2018; 24: 3528-3538
- Genome-wide sequencing of cell-free DNA identifies copy-number alterations that can Be used for monitoring response to immunotherapy in cancer patients.Mol Cancer Ther. 2019; 18: 448-458
- Detection of minimal residual disease using ctDNA in lung cancer: current evidence and future directions.J Thorac Oncol. 2019; 14: 16-24
- Hypermutated circulating tumor DNA: correlation with response to checkpoint inhibitor-based immunotherapy.Clin Cancer Res. 2017; 23: 5729-5736
- Blood-based tumor mutational burden as a predictor of clinical benefit in non-small-cell lung cancer patients treated with atezolizumab.Nat Med. 2018; 24: 1441-1448
- Detection of ultra-rare mutations by next-generation sequencing.Proc Natl Acad Sci U S A. 2012; 109: 14508-14513
- Quantifying ultra-rare pre-leukemic clones via targeted error-corrected sequencing.Leukemia. 2015; 29: 1608-1611
- Role of minimal residual disease testing in acute Myeloid leukemia.Clin Lab Med. 2021; 41: 467-483
- A public resource facilitating clinical use of genomes.Proc Natl Acad Sci U S A. 2012; 109: 11920-11927
- The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.Nature. 2012; 483: 603-607
- Extensive sequencing of seven human genomes to characterize benchmark reference materials.Sci Data. 2016; 3: 160025
- An open resource for accurately benchmarking small variant and reference calls.Nat Biotechnol. 2019; 37: 561-566
Article info
Publication history
Published online: August 22, 2022
Identification
Copyright
© 2022 Elsevier Inc. All rights reserved.
