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- Global, regional, and national burden of multiple sclerosis 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016.Lancet Neurol. 2019; 18: 269-285
- Multiple sclerosis.Lancet. 2018; 391: 1622-1636
- Clinical presentation, course, and prognosis of multiple sclerosis in adults.(Available at:) (Accessed March 11, 2020)
- Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria.Lancet Neurol. 2018; 17: 162-173
- Incidental MRI anomalies suggestive of multiple sclerosis: the radiologically isolated syndrome.Neurology. 2009; 73: 1714
- Anomalies characteristic of central nervous system demyelination: radiologically isolated syndrome.Neurol Clin. 2018; 36: 59-68
- CSF examination still has value in the diagnosis of MS - Commentary.Mult Scler. 2016; https://doi.org/10.1177/1352458516642033
- Cerebrospinal fluid in the diagnosis of multiple sclerosis: a consensus report.J Neurol Neurosurg Psychiatry. 1994; https://doi.org/10.1136/jnnp.57.8.897
- The utility of cerebrospinal fluid analysis in patients with multiple sclerosis.Nat Rev Neurol. 2013; https://doi.org/10.1038/nrneurol.2013.41
- Recommended standard of cerebrospinal fluid analysis in the diagnosis of multiple sclerosis: a consensus statement.Arch Neurol. 2005; 62: 865-870
- The cerebrospinal fluid in multiple sclerosis.Front Immunol. 2019; 10: 1-10
Giovanni G. Cerebrospinal Fluid Analysis in Multiple Sclerosis and Related Disorders. Handbook of Clinical Neurology. (D.S. Goodin, Editor) Elsevier B.V.: Amsterdam, The Netherlands, 2014;122: 681-702. http://doi.org/10.1016/B978-0-444-52001-2.00029-7
- Cerebrospinal fluid analysis in multiple sclerosis diagnosis: an update.Med. 2019; 55: 3-7
- Do oligoclonal bands add information to MRI in first attacks of multiple sclerosis?.Neurology. 2008; https://doi.org/10.1212/01.wnl.0000280576.73609.c6
- Cerebrospinal fluid oligoclonal bands in multiple sclerosis and clinically isolated syndromes: a meta-analysis of prevalence, prognosis and effect of latitude.J Neurol Neurosurg Psychiatry. 2013; https://doi.org/10.1136/jnnp-2012-304695
- Conversion from clinically isolated syndrome to multiple sclerosis: a large multicantre study.Mult Scler. 2015; https://doi.org/10.1177/1352458514568827
- Defining high, medium and low impact prognostic factors for developing multiple sclerosis.Brain. 2015; https://doi.org/10.1093/brain/awv105
- Importance of cerebrospinal fluid analysis in the era of McDonald 2010 criteria.J Neurol. 2016; https://doi.org/10.1007/s00415-016-8302-1
- Cerebrospinal fluid analysis in the diagnosis of multiple sclerosis.Adv Neurol. 2006; 98: 147-160
- Protein electrophoresis in clinical diagnosis.American Society for Clinical Pathology Press, Chicago, Illinois2012
- Cerebrospinal fluid oligoclonal bands in the diagnosis of multiple sclerosis: isoelectric focusing with IgG immunoblotting compared with high-resolution agarose gel electrophoresis and cerebrospinal fluid IgG index.Am J Clin Pathol. 2003; 120: 672-675
- Oligoclonal bands in cerebrospinal fluid: a comparative study of isoelectric focusing, agarose gel electrophoresis and IgG index.Acta Neurol Scand. 2000; 102: 322-325
- Assessment of different methods to detect increased autochthonous production of immunoglobulin G and oligoclonal immunoglobulins in multiple sclerosis.Am J Clin Pathol. 1992; 97: 858-860
College of American Pathologists. Cerebrospinal fluid chemistry and oligoclonal bands (M-B 2019). 2019.
- Tumor necrosis factor in serum and cerebrospinal fluid of patients with multiple sclerosis.Ann Neurol. 1989; 26: 787-789
- Comparison of seven formulae and isoelectrofocusing for determination of intrathecally produced IgG in neurological diseases.Ann Clin Biochem. 1992; 29: 405-410
- Can CSF biomarkers predict future MS disease activity and severity?.Mult Scler J. 2020; 26: 582-590
- Principles of albumin and IgG analyses in neurological disorders. III. evaluation of igg synthesis within the central nervous system in multiple sclerosis.Scand J Clin Lab Invest. 1977; 37: 397-401
- Intrathecal oligoclonal IgG synthesis in multiple sclerosis.J Neuroimmunol. 2013; 262: 1-10
- Treatment of neuromyelitis optica: state-of-the-art and emerging therapies.Nat Rev Neurol. 2014; https://doi.org/10.1038/nrneurol.2014.141
- Aquaporin 4 and neuromyelitis optica.Lancet Neurol. 2012; https://doi.org/10.1016/S1474-4422(12)70133-3
- Myelin oligodendrocyte glycoprotein antibody-associated disorders: toward a new spectrum of inflammatory demyelinating CNS disorders?.Front Immunol. 2018; 9: 1-12
- Free kappa light chains in cerebrospinal fluid as a biomarker to assess risk conversion to multiple sclerosis.Mult Scler J Exp Transl Clin. 2015; 1 (205521731562093)
- CSF isoelectrofocusing in a large cohort of MS and other neurological diseases.Eur J Neurol. 2004; 11: 525-529
- Clinical use of κ free light chains index as a screening test for multiple sclerosis.Lab Med. 2020; https://doi.org/10.1093/labmed/lmz073
- The role of regulatory T cells in multiple sclerosis.Nat Clin Pract Neurol. 2008; 4: 384-398
- Deciphering the role of B cells in multiple sclerosis—towards specific targeting of pathogenic function.Int J Mol Sci. 2017; 18https://doi.org/10.3390/ijms18102048
- The persisting significance of oligoclonal bands in the dawning era of kappa free light chains for the diagnosis of multiple sclerosis.Int J Mol Sci. 2018; 19https://doi.org/10.3390/ijms19123796
- Free light chains in the CSF in multiple sclerosis.J Neurol. 1987; https://doi.org/10.1007/BF00314285
- Validation of kappa free light chains as a diagnostic biomarker in multiple sclerosis and clinically isolated syndrome: a multicenter study.Mult Scler. 2016; 22: 502-510
- Elevated levels of kappa free light chains in CSF support the diagnosis of multiple sclerosis.J Neurol. 2008; 255: 1508-1514
- Reference values for CSF-igm, CSF-igm/s-igm ratio and igm index, and its application to patients with multiple sclerosis and aseptic meningoencephalitis.Scand J Clin Lab Invest. 1984; 44: 7-12
- Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis.Neurology. 2019; 93: e1439-e1451
- Intrathecal IgM synthesis predicts the onset of new relapses and a worse disease course in MS.Neurology. 2002; 59: 555-559
- Intrathecal IgM production at clinical onset correlates with a more severe disease course in multiple sclerosis.J Neurol Neurosurg Psychiatry. 2006; 77: 953-955
- Evaluation of no evidence of disease activity in a 7-year longitudinal multiple sclerosis cohort.JAMA Neurol. 2015; 72: 152-158
- The cerebrospinal fluid in multiple sclerosis: far beyond the bands.Einstein (Sao Paulo). 2017; 15: 100-104
- Immunopathology of multiple sclerosis.Nat Rev Immunol. 2015; 15: 545-558
- Cerebrospinal fluid and serum protein levels of tumour necrosis factor-alpha (TNF-α), interleukin-6 (IL-6) and soluble interleukin-6 receptor (sIL-6R gp80) in multiple sclerosis patients.Cytokine. 2002; 20: 86-88
- IL-6 and CCL2 levels in CSF are associated with the clinical course of MS: implications for their possible immunopathogenic roles.J Neuroimmunol. 2006; 175: 176-182
- Characteristic cerebrospinal fluid cytokine/chemokine profiles in neuromyelitis optica, relapsing remitting or primary progressive multiple sclerosis.PLoS One. 2013; 8https://doi.org/10.1371/journal.pone.0061835
- CSF inflammation and axonal damage are increased and correlate in progressive multiple sclerosis.Mult Scler J. 2013; 19: 877-884
- CXCL13 is a biomarker of inflammation in multiple sclerosis, neuromyelitis optica, and other neurological conditions.Mult Scler J. 2013; 19: 1204-1208
- Cerebrospinal fluid CXCL13 in clinically isolated syndrome patients: association with oligoclonal IgM bands and prediction of multiple sclerosis diagnosis.J Neuroimmunol. 2015; https://doi.org/10.1016/j.jneuroim.2015.04.011
- Increased neurofilament light chain blood levels in neurodegenerative neurological diseases.PLoS One. 2013; 8https://doi.org/10.1371/journal.pone.0075091
- Neurofilament protein in cerebrospinal fluid: a potential marker of activity in multiple sclerosis.J Neurol Neurosurg Psychiatry. 1998; 64: 402-404
- Assessing tissue damage in multiple sclerosis: a biomarker approach.Acta Neurol Scand. 2014; 130: 81-89
- Neurofilament light as a prognostic marker in multiple sclerosis.Mult Scler. 2010; 16: 287-292
- Cerebrospinal fluid biomarkers as a measure of disease activity and treatment efficacy in relapsing-remitting multiple sclerosis.J Neurochem. 2017; 141: 296-304
- Cognitive impairment in early stages of multiple sclerosis is associated with high cerebrospinal fluid levels of chitinase 3-like 1 and neurofilament light chain.Eur J Neurol. 2018; 25: 1189-1191
- Glial fibrillary acidic protein in CSF of multiple sclerosis patients: relation to neurological deficit.J Neurol Sci. 1995; 133: 61-65
- Markers for different glial cell responses in multiple sclerosis: clinical and pathological correlations.Brain. 2002; 125: 1462-1473
- Neurofilament light protein and glial fibrillary acidic protein as biological markers in MS.Neurology. 2003; https://doi.org/10.1212/01.WNL.0000098880.19793.B6
- The only certain measure of the effectiveness of multiple sclerosis therapy is cerebrospinal neurofilament level - YES.Mult Scler. 2015; 21: 1239-1240