Review Article| Volume 38, ISSUE 3, P527-537, September 2018

Liquid Chromatography–Mass Spectrometry Education for Clinical Laboratory Scientists


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        • Vogeser M.
        Mass Spectrometry in the clinical laboratory—challenges for quality assurance.
        Spectroscopy. 2015; 13: 14-19
      1. Education and expense: the barriers to mass spectrometry in clinical laboratories? Technology networks. 2015. Available at: Accessed May 2, 2018.

        • Paxton A.
        MALDI in microbiology: set to stun?.
        CAP Today. 2015;
        • Tan K.E.
        • Ellis B.C.
        • Lee R.
        • et al.
        Prospective evaluation of a matrix-assisted laser desorption ionization-time of flight mass spectrometry system in a hospital clinical microbiology laboratory for identification of bacteria and yeasts: a bench-by-bench study for assessing the impact on time to identification and cost-effectiveness.
        J Clin Microbiol. 2012; 50: 3301-3308
        • Romano F.
        The day the typesetting industry died.
        WhatTheyThink, Market Intelligence for Printing and Publishing, 2011 (Available at:) (Accessed May 2, 2018)
      2. American Association for Clinical Chemistry online certificate programs, Introductory Liquid Chromatography Mass Spectrometry for the Clinical Laboratory and LC-MS/MS Troubleshooting for the Clinical Laboratory. Available at: Accessed May 2, 2018.

      3. Mass Spectrometry Applications to the Clinical Laboratory (MSACL) Short Courses at United States and European meetings. Available at: Accessed May 2, 2018.

      4. American Society for Mass Spectrometry (ASMS) Annual Meeting Short Courses, 02 Clinical Diagnostics: Innovation, Validation, Implementation and Operation by Mass Spectrometry. Available at: Accessed May 2, 2018.

      5. Ritchie J, Botelho J, Vesper H. Performing clinical testing using mass spectrometry – hands-on training. Emory University/CDC Joint Center for Mass Spectrometry and Advanced Technology. Available at: Accessed May 2, 2018.

        • Stoll D.R.
        Resources for lc practitioners in 2017: what’s on your bookshelf and in your web browser?.
        LCGC. 2017; 35: 854-861
        • Dickerson J.
        • Mathias P.
        Making a case for automated data review.
        Clin Lab News, Washington, DC2016
        • Alexander K.
        • Terrell A.R.
        Automated review of mass spectrometry results can we achieve autoverification?.
        Clin Lab News, 2015
        • Henderson C.M.
        • Shulman N.J.
        • MacLean B.
        • et al.
        Skyline performs as well as vendor software in the quantitative analysis of serum 25-hydroxy vitamin D and vitamin D binding globulin.
        Clin Chem. 2018; 64: 408-410
      6. Panorama: repository software for targeted mass spectrometry assays from skyline. Available at: Accessed April 2, 2018.

        • Zabell A.
        • Stone J.A.
        • Julian R.K.
        Using big data for LC-MS/MS quality analysis.
        Clin Lab News, Washington, DC2017
        • Bittremieux W.
        • Willems H.
        • Keighterman P.
        • et al.
        iMonDB: mass spectrometry quality control through instrument monitoring.
        J Proteome Res. 2015; 14: 2360-2366
        • Dogu E.
        • Mohammad-Taheri S.
        • Abbatiello S.E.
        • et al.
        MSstatsQC: longitudinal system suitability monitoring and quality control for targeted proteomic experiments.
        Mol Cell Proteomics. 2017; 16: 1335-1347