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Research Article| Volume 1, ISSUE 1, P127-150, March 1981

Hematology: Automated White Blood Cell Differential Counting by Flow-Analysis

  • Robert E. Miller
    Correspondence
    Department of Laboratory Medicine The Johns Hopkins Hospital Disp. 592 Baltimore, Maryland 21205.
    Affiliations
    Deputy Director, Department of Laboratory Medicine, The Johns Hopkins Hospital; Assistant Professor of Pathology (Laboratory Medicine) and Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland
    Search for articles by this author
DOI:https://doi.org/10.1016/S0272-2712(18)31120-X
Hematology: Automated White Blood Cell Differential Counting by Flow-Analysis
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      Technology assessments performed in conjunction with the development and introduction of flow-analysis automated white blood cell differential counters emphasize that methods comparisons in laboratory medicine are difficult when there are marked differences in analytical precision between methods and when the sources of methodologic errors are incompletely understood or inadequately measured and controlled. However, automation of the white blood cell differential count provides a useful example of how careful assessment of an existing laboratory test methodology and consideration of unmet clinical needs assist in defining performance objectives as well as delineating probable performance limits for new and evolving technologies.
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      DOI: https://doi.org/10.1016/S0272-2712(18)31120-X

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      © 1981 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

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