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Theophylline and salicylates, drugs that are frequently prescribed for pediatric patients, have a well-defined range of optimal therapeutic concentration; therapeutic monitoring of these agents is accurate and specific. In contrast, despite the widespread use of acetaminophen, its therapeutic range is not well established; however, serious toxicity from overdose is predictable from the serum concentration.
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© 1981 Elsevier Inc. Published by Elsevier Inc. All rights reserved.