Research Article| Volume 1, ISSUE 3, P541-545, September 1981

Tricyclic Antidepressants and Lithium

  • James M. Byers III
    Corresponding author: Department of Pathology, University of Arizona Health Sciences Center, Tucson, Arizona 85724
    Associate Professor of Pathology, University of Arizona; Chief, Toxicology Section, University Hospital Clinical Laboratories, Tucson, Arizona
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      Although difficulty in correlating plasma levels of tricyclic antidepressants with therapeutic outcome has been reported, therapeutic monitoring can be helpful in the management of selected depressed patients. The greater toxic potential of lithium is a pressing and clear indication for therapeutic monitoring in manic patients.
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