Research Article| Volume 1, ISSUE 4, P767-774, December 1981

The Assessment of Protein Nutrition in the Hospitalized Patient

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      Inadequate protein intake or physiological stress can result in protein malnutrition, either marasmus or kwashiorkor, in the hospitalized patient. Composition analysis to determine somatic protein stores and function assessment to evaluate visceral protein production are critical in charting a course for the nutritional management of a patient. Methods to monitor the response of a patient to nutritional support are presented.
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        • Bistrian B.R.
        • Blackburn G.L.
        • Hallowell E.
        • et al.
        Protein status of general surgical patients.
        J.A.M.A. 1974; 230: 858
        • Blackburn G.L.
        • Thornton P.A.
        Nutritional assessment of the hospitalized patient.
        Med. Clin. North Am. 1979; 63: 1103
        • Blackburn G.L.
        • Bistrian B.R.
        • Maini B.S.
        Nutritional and metabolic assessment of the hospitalized patients.
        J. Parent. Ent. Nutr. 1977; 1: 11-22
        • Bleiler R.A.
        • Schedl H.P.
        Creatinine excretion: Variability and relationship to diet and body size.
        J. Lab. Clin. Med. 1962; 59: 945
        • Brozak J.
        • Grande R.
        • Anderson J.
        • et al.
        Densitometrie analysis of body composition.
        Ann. N.Y. Acad. Sei. 1963; 110: 113
        • Cahill Jr., G.F.
        Starvation in man.
        N. Engl. J. Med. 1970; 282: 668
        • Cahill Jr., G.F.
        Starvation in man.
        Clin. Endocrinol. Metab. 1976; 5: 397-415
        • Forbes G.B.
        • Bruining G.J.
        Urinary creatinine excretion and lean body mass.
        Am. J. Clin. Nutr. 1976; 29: 1359
        • Forbes G.B.
        • Hursh J.B.
        Age and sex trends in lean body mass calculated from 40K measurements.
        Ann. N.Y. Acad. Sei. 1963; 110: 255
      1. Goldman, R. F, and Buskirk, F. R.: A method for underwater weighing and die determination of body density. In Brozek, J, and Heuschel, A. (eds): Techniques for Measuring Body Composition. National Academy of Sciences, National Research Council, 1961

        • Harvey K.B.
        • Ruggiero J.A.
        • Regan C.S.
        • et al.
        Hospital morbility-mortality risk factors using nutritional assessment.
        Clin. Res. 1978; 26: 581A
        • Ingenbleek Y.
        • Van Den Schrieck A.G.
        • De Nayer P.
        • et al.
        The role of retinol binding protein in protein calorie malnutrition.
        Metabolism. 1975; 24: 633
        • Mancini G.
        • Carbonara A.O.
        • Heremans J.F.
        Immunochemical quantitation of antigens by radial immunodiffusion.
        Immunochem. 1965; 2: 235
        • Meakins J.L.
        • Pietsch J.B.
        • Bubenick O.
        Delayed hypersensitivity: Indicator of acquired failure of host defence in infection and trauma.
        Ann. Surg. 1977; 186: 241-250
        • Moore F.D.
        Metabolic care of the surgical patient.
        W. B. Saunders Co, Philadelphia1959
        • Mullen J.L.
        • Buzby G.P.
        • Matthews D.C.
        • et al.
        Reduction of operative morbidity and mortality by combined pre-operative and post-operative nutritional support.
        Ann. Surg. 1980; 192: 604
        • O’Connell R.C.
        • Morgan A.P.
        • Aoki T.T.
        • et al.
        Nitrogen conservation in starvation: Graded response to intravenous glucose.
        J. Clin. Endocrinol. Metab. 1974; 39: 355
        • Olson R.
        The effect of variations in protein and calorie-intake on the rate of recovery and selected physiological responses in Thai children with protein-caloric malnutrition.
        in: Olson R.E. Protein-Calorie Malnutrition. Academic Press, New York1975
        • Peterson P.A.
        Demonstration in serum of two physiological forms of human retinol binding protein.
        Eur. J. Clin. Invest. 1971; 1: 437
        • Picou D.
        • Taylor-Roberts T.
        The measurement of total protein synthesis and catabolism and nitrogen turnover in infants in different nutritional states and receiving different amounts of dietary protein.
        Clin. Sei. Mol. Med. 1969; 36: 283
        • Rhoads J.E.
        • Alexander C.E.
        Nutritional problems of surgical patients.
        Ann. N.Y. Acad. Sei. 1955; 63: 268-275
        • Rosenoer V.M.
        • Skillman J.J.
        • Hastings P.R.
        • et al.
        Albumin synthesis and nitrogen balance in post-operative patients.
        Surgery. 1980; 87: 305
        • Rothschild M.A.
        • Oratz M.
        • Schreiber S.S.
        Albumin synthesis.
        N. Engl. J. Med. 1972; 286: 748
        • Skillman J.J.
        • Rosemoer V.M.
        • Smith P.C.
        • et al.
        Improved albumin synthesis in post-operative patients by amino acid infusion.
        N. Engl. J. Med. 1976; 295: 1037
        • Ward M.W.N.
        • Owens C.W.I.
        • Rennie M.J.
        Nitrogen estimation in biological samples by use of chemiluminescence.
        Clin. Chem. 1980; 26: 1336
        • Watkins P.J.
        The effect of ketone bodies on the determination of creatinine.
        Clin. Chem. Acta. 1967; 18: 191
        • Winterer J.
        • Bistrian G.R.
        • Bilmazes C.
        • et al.
        Whole body protein turnover studied with 15N-glycine, and muscle protein breakdown in mildly obese subjects during a protein-sparing diet and a brief total fast.
        Metabolism. 1980; 29: 575