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Clinical evidence of vitamin A deficiency or toxicity is discussed. Current methods used to assess vitamin A status are critiqued; of these, high performance liquid chromatography appears to have the greatest potential for sensitive, specific, and accurate measurements of vitamin A in biologic samples.
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- The determination of vitamin A and carotene in small quantities of blood serum.J. Biol. Chem. 1946; 166: 177
- Determination of serum phytofluene and retinol.Clin. Chem. Acta. 1973; 48: 329
- Determination of vitamin A by conversion to anhydro vitamin A.Analyst. 1957; 82: 751
- Color reactions attributed to vitamin A.Biochem. J. 1926; 20: 497
- Determination of serum retinol (vitamin A) by high-speed liquid chromatography.Clin. Chem. 1976; 22: 1593
- Simultaneous determination of retinol and retinylesters in serum or plasma by reverse-phase high-performance liquid chromatography.Clin. Chem. 1978; 24: 1920
- Colorimetric determination of vitamin A and its derivatives with trifluoroacetic acid.Anal. Chem. 1964; 36: 114
- Enzymatic reduction of retinal to retinol in rat intestinal mucosa.Fed. Proc. 1967; 26: 849
- A new, rapid fluorometric determination of retinol in serum.Invest. Ophthalmol. 1975; 14: 125
- Why such high serum levels of vitamin A?.Pediatrics. 1975; 55 (letter): 899
Garry, P. J.: Nutritional assessment of a healthy aged population. Unpublished data.
- Plasma vitamin A assay by fluorometry and use of a silicic acid column technique.Clin. Chem. 1970; 16: 766
- Retinol-binding protein, prealbumin and vitamin A transport.Prog. Clin. Biol. Res. 1976; 5: 313
- Vitamin A transport and retinol binding protein metabolism.Vitam. Horm. 1974; 32: 167
- The intestinal absorption and metabolism of vitamin A and /3-carotene in man.J. Clin. Invest. 1966; 45: 1615
- Plasma vitamin A and E levels in children with familial type II hyperlipoproteinemia during therapy with diet and cholestyramine resin.Pediatrics. 1974; 54: 51
- A fluorometric micromethod for serum A.Amer. J. Clin. Pathol. 1968; 50: 525
- A method for the fluorometric determination of vitamin A.Scandinav. J. Clin. Lab. Invest. 1966; 18: 679
- Automated fluorometric assay of serum vitamin A.Internat. J. Nutr. Res. 1973; 43: 127
- Retinol-binding protein: The transport protein for vitamin A in human plasma.J. Clin. Invest. 1968; 47: 2025
- Microdetermination of vitamin A and carotenoids in blood and tissue. Methods in Biochemical Analysis.Volume 15. Interscience Publishers, New York1967
- Colorimetric estimation of vitamin A and /3-carotene with antimony pentachloride.J. Vitaminai. 1960; 6: 158
- Regulation of retinol-binding protein metabolism by vitamin A status in the rat.J. Biol. Chem. 1972; 247: 2542
- Macro- and micromethods for the determination of serum vitamin A using trifluoroacetic acid.J. Nutr. 1963; 79: 454
- Characteristics of a vitamin A transporting protein complex occurring in human serum.J. Biol Chem. 1971; 246: 34
- Vitamin A and protein metabolism.J. Agr. Food Chem. 1972; 20: 1133
- The effects of diseases of the liver, thyroid, and kidneys on the transport of vitamin A in human plasma.J. Clin. Invest. 1971; 50: 2426
- Vitamin A transport in human vitamin A toxicity.N. Engl. J. Med. 1976; 294: 805
- Serum vitamin A, retinol-binding protein, and prealbumin concentrations in protein-calorie malnutrition. II. Treatment including supplemental vitamin A.Amer. J. Clin. Nutr. 1973; 26: 982
- Serum vitamin A, retinol-binding protein, and prealbumin concentrations in protein-calorie malnutrition. I. A functional defect in hepatic retinol release.Amer. J. Clin. Nutr. 1973; 26: 973
- Radioimmunoassay of human plasma retinol-binding protein.J. Clin. Invest. 1970; 49: 1754
- Depressed plasma retinol-binding protein levels in cystic fibrosis.J. Lab. Clin. Med. 1972; 80: 423
- Zinc: A trace element essential in vitamin A metabolism.Science. 1973; 181: 954
- The effect of zinc deficiency on the metabolism of retinol-binding protein in the rat.J. Lab. Clin. Med. 1974; 84: 692
- The estimation of serum vitamin A with activated glycerol dichlorohydrin.J. Biol. Chem. 1947; 171: 617
- Recent advances in the metabolism of vitamin A.J. Sei. Ind. Res. 1972; 31: 581
- Fluorometric determination of vitamin A in human blood and liver.Biochem. Med. 1971; 5: 67
© 1981 Elsevier Inc. Published by Elsevier Inc. All rights reserved.