Research Article| Volume 2, ISSUE 1, P65-85, March 1982

Blood Transfusion in Heart Surgery

  • John D. Milam
    Corresponding author: Department of Pathology, St. Luke’s Episcopal Hospital, Texas Medical Center, Houston, Texas 77030
    Clinical Associate Professor of Pathology, Baylor College of Medicine and University of Texas Medical School at Houston; Associate Director, Department of Pathology, and Director of Blood Bank and Transfusion Service, St. Luke’s Episcopal Hospital and the Texas Heart Institute, Houston, Texas
    Search for articles by this author
      This paper is only available as a PDF. To read, Please Download here.
      During the past three decades, hemotherapy and cardiopulmonary bypass techniques have changed drastically in conjunction with advances in open heart surgery. Today, an active cardiovascular service exerts an unyielding influence on the activities of the supporting blood bank and transfusion service. Hematologic alterations and blood transfusion requirements of patients undergoing cardiovascular surgery are discussed.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.


      Subscribe to Clinics in Laboratory Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Baroldi G.
        • Milam J.D.
        • Wukasch D.C.
        • et al.
        Myocardial cell damage in “stone hearts”.
        J. Mol. Cell. Cardiol. 1974; 6: 395-399
        • Bennett S.H.
        • Geelhoed G.W.
        • Aaron R.K.
        • et al.
        Pulmonary injury resulting from perfusion with stored bank blood in the baboon and dog.
        J. Surg. Res. 1972; 13: 295-306
        • Cooley D.A.
        • Beall Jr., A.C.
        • Grondin P.
        Open-heart operations with disposable oxygenators, 5 per cent dextrose prime, and normothermia.
        Surgery. 1962; 52: 713-719
        • Dhurandhar H.N.
        • Brown C.
        • Barrett J.
        • et al.
        Pulmonary structural changes following microembolism and blood transfusion.
        Arch. Pathol. Lab. Med. 1979; 103: 335-340
        • Garcia-Rinaldi R.
        • Gallagher M.W.
        • Rea J.E.
        • et al.
        The topical myocardial cooling device: Correlation of its effectiveness with method of cannulation and core temperature of the patient.
        Cardiovascular Diseases, Bull. Texas Heart Institute. 1981; 8: 394-404
        • Goldiner P.L.
        • Howland W.S.
        • Ray C.
        Filter for prevention of microembolism during massive transfusions.
        Anesth. Analg. 1972; 51: 717-725
        • Jenevein E.P.
        • Weiss D.L.
        Platelet microemboli associated with massive blood transfusion.
        Am. J. Pathol. 1964; 45: 313-325
        • Liotta D.
        Myocardial protection during cardiopulmonary bypass.
        Cardiovascular Diseases, Bull. Texas Heart Institute. 1977; 4: 30-36
        • Litwin M.S.
        • Relihan M.
        • Sillin L.
        Filtration characteristics of Dacron wool (Swank) blood transfusion filters.
        South. Med. J. 1975; 68: 694-698
        • Malloy K.P.
        • Wukasch D.C.
        • Reed C.C.
        • et al.
        Fat embolism during cardiopulmonary by pass: A preliminary investigation.
        AmSect Proc. 1974; 2: 17-19
        • Milam J.D.
        • Austin S.F.
        Red cell salvage in open-heart surgery.
        in: Hemotherapy in Trauma and Surgery. American Association of Blood Banks, Washington, D.C.1979: 67-75
        • Milam J.D.
        • Austin S.F.
        • Martin R.F.
        • et al.
        Alteration of coagulation and selected clinical chemistry parameters in patients undergoing open heart surgery without transfusions.
        Am. J. Clin. Pathol. 1981; 76: 155-162
        • Miller W.V.
        Technical Methods and Procedures of the American Association of Blood Banks.
        Edition 6. J. B. Lippincott Co., Philadelphia1974
      1. Monaghan, P. W.: Personal communication. July 1981.

        • Moseley R.V.
        • Doty D.B.
        Changes in the filtration characteristics of stored blood.
        Ann. Surg. 1970; 171: 336-342
      2. Reaves, W. H., Milam, J. D., Clark, D. K., et al.: Effect of washing blood salvaged from oxygenator following extracorporeal circulation. AmSect Proc., 1976, pp. 80–83.

        • Reul G.J.
        • Greenberg S.D.
        • Lefrak E.A.
        • et al.
        Prevention of post-traumatic pulmonary insufficiency.
        Arch. Surg. 1973; 106: 386-394
        • Solis R.T.
        • Gibbs M.B.
        Filtration of the microaggregates in stored blood.
        Transfusion. 1972; 12: 245-250
        • Wukasch D.C.
        • Reul G.J.
        • Milam J.D.
        • et al.
        The “stone heart” syndrome.
        Surgery. 1972; 72: 1071-1080
        • Wukasch D.C.
        • Malloy K.P.
        • Rubio P.A.
        • et al.
        Fat embolization resulting from median sternotomy.
        Tex. Med. 1975; 71: 35-41