Advertisement
Research Article| Volume 4, ISSUE 1, P99-121, March 1984

Download started.

Ok

Controversies in Antimicrobial Susceptibility Testing

  • Frank G. Witebsky
    Correspondence
    Corresponding author: Microbiology Service, Department of Clinical Pathology, National Institutes of Health, Bldg. 10, Room 4D-07, Bethesda, Maryland 20205
    Affiliations
    Assistant Chief, Microbiology Service, Department of Clinical Pathology, Clinical Center, National Institutes of Health, Bethesda, Maryland
    Search for articles by this author
DOI:https://doi.org/10.1016/S0272-2712(18)30945-4
Controversies in Antimicrobial Susceptibility Testing
Previous ArticleLimitations and Value of Aspiration Cytology
Next ArticleThe Contributions of Electron Microscopy in the Diagnosis and Histogenesis of Controversial Neoplasms
      This paper is only available as a PDF. To read, Please Download here.
      This article examines a number of areas of disagreement surrounding antimicrobial susceptibility testing and discusses some of the useful susceptibility testing techniques for which no standardized procedures have been established.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.

      Subscribe:

      Subscribe to Clinics in Laboratory Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Register: Create an account
      Institutional Access: Sign in to ScienceDirect

      References

      1. American Society of Hospital Pharmacists: American Hospital Formulary Service. Bethesda, Maryland, American Society of Hospital Pharmacists, updated annually.

        • Anhalt J.P.
        • Sabath L.D.
        • Barry A.L.
        Special tests: Bactericidal activity, activity of antimicrobics in combination, and detection of β-lactamase production.
        in: Lennette E.H. Manual of Clinical Microbiology. Edition 3. American Society for Microbiology, Washington, D.C.1980: 478-484
        • Barry A.L.
        A system for reporting quantitative antimicrobic susceptibility test results.
        Am. J. Clin. Pathol. 1979; 72: 864-868
        • Barry A.L.
        • Jones R.N.
        • Gavan T.L.
        Evaluation of the Micro-Media System for quantitative antimicrobial drug susceptibility testing: A collaborative study.
        Antimicrob. Agents Chemother. 1978; 13: 61-69
        • Barry A.L.
        • Thornsberry C.
        Susceptibility testing: Diffusion test procedures.
        in: Lennette E.H. Manual of Clinical Microbiology. Edition 3. American Society for Microbiology, Washington, D.C.1980: 463-474
        • Barry A.L.
        • Thornsberry C.
        • Jones R.N.
        • et al.
        Reassessment of the “class” concept of disk susceptibility testing. Cephalothin disks versus minimal inhibitory concentrations with eleven cephalosporins.
        Am. J. Clin. Pathol. 1978; 70: 909-913
        • Bartlett R.C.
        • Rutz C.A.
        • Konopacki N.
        Cost effectiveness of quality control in bacteriology.
        Am. J. Clin. Pathol. 1982; 77: 184-190
        • Bauer A.W.
        • Kirby W.M.M.
        • Sherris J.C.
        • et al.
        Antibiotic susceptibility testing by a standardized single disc method.
        Am. J. Clin. Pathol. 1966; 45: 493-496
        • Blair H.C.
        • Cleary T.J.
        Susceptibility testing of multidrug-resistant Staphylococcus aureus with the Sceptor microdilution system.
        J. Clin. Microbiol. 1983; 18: 194-196
        • Busch E.
        • Blazevic D.J.
        Serum dilution tests for determination of antibacterial activity.
        Clin. Microbiol. Newsletter. 1979; 1: 1-3
        • Eliopoulos G.M.
        • Moellering Jr., R.C.
        Antibiotic synergism and antimicrobial combinations in clinical infections.
        Rev. Infect. Dis. 1982; 4: 282-293
        • Ellner P.D.
        • Neu H.C.
        The inhibitory quotient. A method for interpreting minimum inhibitory concentration data.
        J.A.M.A. 1981; 246: 1575-1578

      13. Ericsson, H. M., and Sherris, J. C.: Antibiotic sensitivity testing. Report of an international collaborative study. Acta Pathol. Microbiol. Scand. [B], Suppl. 217, 1971.

        • Finegold S.M.
        Anaerobic Bacteria in Human Disease.
        Academic Press, New York1977
        • Gill V.J.
        • Manning C.B.
        • Ingalls C.M.
        Correlation of penicillin minimum inhibitory concentrations and penicillin zone edge appearance with staphylococcal betalactamase production.
        J. Clin. Microbiol. 1981; 14: 437-440
        • Hansen S.L.
        • Freedy P.K.
        Concurrent comparability of automated systems and commercially prepared microdilution trays for susceptibility testing.
        J. Clin. Microbiol. 1983; 17: 878-886
        • Isenberg H.D.
        • Washington II, J.A.
        • Balows S.
        • et al.
        Collection, handling, and processing of specimens.
        in: Lennette E.H. Manual of Clinical Microbiology. Edition 3. American Society for Microbiology, Washington, D.C.1980: 60-61
        • Jordan G.W.
        • Kawachi M.M.
        Analysis of serum bactericidal activity in endocarditis, osteomyelitis, and other bacterial infections.
        Medicine. 1981; 60: 49-61
        • King T.C.
        • Schlesinger D.
        • Krogstad D.J.
        The assessment of antimicrobial combinations.
        Rev. Infect. Dis. 1981; 3: 627-633
        • Klastersky J.
        • Daneau D.
        • Swings G.
        • et al.
        Antibacterial activity in serum and urine as a therapeutic guide in bacterial infections.
        J. Infect. Dis. 1974; 129: 187-193
        • Kramer B.S.
        • Pizzo P.A.
        • Robichaud K.M.
        • et al.
        Role of serial microbiologic surveillance and clinical evaluation in the management of cancer patients with fever and granulocytopenia.
        Am. J. Med. 1982; 72: 561-568
        • Krogstad D.J.
        • Moellering Jr., R.C.
        Combinations of antibiotics, mechanisms of interaction against bacteria.
        in: Lorian V. Antibiotics in Laboratory Medicine. Williams and Wilkins Co., Baltimore1980: 298-341
        • Martin Jr., W.J.
        Is routine susceptibility testing of anaerobes necessary?.
        Clin. Microbiol. Newsletter. 1981; 3: 111-112
        • Marymont Jr., J.H.
        • Marymont J.
        Laboratory evaluation of antibiotic combinations: A review of methods and problems.
        Lab. Med. 1981; 12: 47-55
        • Matsen J.M.
        Rapid reporting of results—Impact on patient, physician, and laboratory.
        in: Tilton R.C. Rapid Methods and Automation in Microbiology. American Society for Microbiology, Washington, D.C.1982: 98-102
        • McGinnis M.R.
        Laboratory Handbook of Medical Mycology.
        Academic Press, New York1980: 411-446
        • Moellering Jr., R.C.
        Antimicrobial synergism—An elusive concept.
        J. Infect. Dis. 1979; 140: 639-641
        • Morbidity and Mortality Weekly Report
        Spectinomycin-resistant β-lactamase-producing Neisseria gonorrhoeae—England.
        Morbid. Mortal. Weekly Rep. 1982; 31: 496-501
        • Morbidity and Mortality Weekly Report
        Penicillin-resistant gonorrhea—North Carolina.
        Morbid. Mortal. Weekly Rep. 1983; 32: 273-275
        • Murray P.R.
        • Jorgensen J.H.
        Quantitative susceptibility test methods in major United States medical centers.
        Antimicrob. Agents Chemother. 1981; 20: 66-70
        • National Committee for Clinical Laboratory Standards
        Performance Standards for Antimicrobic Disc Susceptibility Tests. Approved Standard: ASM-2. Edition 2.
        National Committee for Clinical Laboratory Standards, Villanova, Pennsylvania1979
        • National Committee for Clinical Laboratory Standards
        Performance Standards for Antimicrobic Disc Susceptibility Tests. First Supplement.
        National Committee for Clinical Laboratory Standards, Villanova, Pennsylvania1981
        • National Committee for Clinical Laboratory Standards
        Performance Standards for Antimicrobic Disc Susceptibility Tests. Second Informational Supplement.
        National Committee for Clinical Laboratory Standards, Villanova, Pennsylvania1982
        • National Committee for Clinical Laboratory Standards
        Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically. Tentative Standard: M7-T.
        National Committee for Clinical Laboratory Standards, Villanova, Pennsylvania1983
        • National Committee for Clinical Laboratory Standards
        Tentative Standard Reference Agar Dilution Procedure for Antimicrobial Susceptibility Testing of Anaerobic Bacteria. Tentative Standard: Mll-T.
        National Committee for Clinical Laboratory Standards, Villanova, Pennsylvania1982
        • Norden C.W.
        • Wentzel H.
        • Keleti E.
        Comparison of techniques for measurement of in vitro antibiotic synergism.
        J. Infect. Dis. 1979; 140: 629-633
        • Pearson R.D.
        • Steigbigel R.T.
        • David H.T.
        • et al.
        Method for reliable determination of minimal lethal antibiotic concentrations.
        Antimicrob. Agents Chemother. 1980; 18: 699-708
        • Pizzo P.
        • Robichaud K.J.
        • Gill F.A.
        • et al.
        Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia.
        Am. J. Med. 1982; 72: 101-111
        • Preston D.A.
        • Jones R.N.
        • Barry A.L.
        • et al.
        Comparison of the antibacterial spectra of cephalexin and cefaclor with those of cephalothin and newer cephalosporins: Reevaluation of the class representative concept of susceptibility testing.
        J. Clin. Microbiol. 1983; 17: 1156-1158
        • Radetsky M.S.
        • Johansen T.L.
        • Lauer B.A.
        • et al.
        Multiply resistant pneumococcus causing meningitis: Its epidemiology within a day-care centre.
        Lancet. 1981; 2: 771-773
        • Reymann M.T.
        • Bradac J.A.
        • Cobbs C.G.
        • et al.
        Correlation of aminoglycoside dosages with serum concentrations during therapy of serious gram-negative bacillary disease.
        Antimicrob. Agents Chemother. 1979; 16: 353-361
        • Rippon J.W.
        Medical Mycology. The Pathogenic Fungi and the Pathogenic Antinomycetes.
        W. B. Saunders Co., Philadelphia1982: 782-787
        • Rolfe R.D.
        • Finegold S.M.
        Comparative in vitro activity of new beta-lactam antibiotics against anaerobic bacteria.
        Antimicrob. Agents Chemother. 1981; 20: 600-609
        • Rosenblatt J.E.
        Antimicrobial susceptibility testing of anaerobes.
        in: Lorian V. Antibiotics in Laboratory Medicine. Williams and Wilkins Co., Baltimore1980: 114-134
        • Rosenblatt J.E.
        • Murray P.R.
        • Sonnenwirth A.
        • et al.
        Comparison of anaerobic susceptibility results obtained by different methods.
        Antimicrob. Agents Chemother. 1979; 15: 351-355
        • Sabath L.D.
        Staphylococcal tolerance to penicillins and cephalosporins.
        in: Schlessinger D. Microbiology—1979. American Society for Microbiology, Washington, D.C.1979: 299-303
        • Sanders C.C.
        Novel resistance selected by the new expanded-spectrum cephalosporins: A concern.
        J. Infect. Dis. 1983; 147: 585-589
        • Stratton C.W.
        • Weinstein M.P.
        • Reller L.B.
        Correlation of serum bactericidal activity with antimicrobial agent level and minimum bactericidal concentration.
        J. Infect. Dis. 1982; 145: 160-168
        • Sutter V.L.
        • Washington II, J.A.
        Susceptibility testing of anaerobes.
        in: Lennette E.H. Manual of Clinical Microbiology. Edition 3. American Society for Microbiology, Washington, D.C.1980: 475-477
        • Swenson J.M.
        • Thornsberry C.
        • Silcox V.A.
        Rapidly growing mycobacteria: Testing of susceptibility to 34 antimicrobial agents by broth microdilution.
        Antimicrob. Agents Chemother. 1982; 22: 186-192
        • Taylor P.C.
        • Schoenknecht F.D.
        • Sherris J.C.
        • et al.
        Determination of minimum bactericidal concentrations of oxacillin for Staphylococcus aureus: Influence and significance of technical factors.
        Antimicrob. Agents Chemother. 1983; 23: 142-150
        • The Medical Letter
        Handbook of Antimicrobial Therapy.
        The Medical Letter, New Rochelle, New York1982
        • Vestal A.L.
        Procedures for the Isolation and Identification of Mycobacteria. Department of Health, Education, and Welfare Publication No. (CDC) 79-8230.
        Centers for Disease Control, Atlanta, Georgia1975
        • Voss S.R.
        • MacLowry J.D.
        Antibacterial levels in various body fluids in the normal individual.
        in: von Graevenitz A. CRC Handbook Series in Clinical Laboratory Science, Section E: Clinical Microbiology. Vol. 2. CRC Press, Cleveland1977
        • Washington J.A.I.
        Infectious diseases 1979—Antimicrobial susceptibility tests.
        J. Infect. Dis. 1979; 140: 261-263
        • Witebsky F.G.
        • MacLowry J.D.
        • French S.S.
        Broth dilution minimum inhibitory concentrations: Rationale for use of selected antimicrobial concentrations.
        J. Clin. Microbiol. 1979; 9: 589-595

      Article info

      Identification

      DOI: https://doi.org/10.1016/S0272-2712(18)30945-4

      Copyright

      © 1984 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

      ScienceDirect

      Access this article on ScienceDirect

      The content on this site is intended for healthcare professionals.


      We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the Cookie Preference Center for this site.
      Copyright © 2023 Elsevier Inc. except certain content provided by third parties.


      RELX