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Research Article| Volume 4, ISSUE 4, P787-801, December 1984

Prostaglandins In Human Disease

  • Laurence M. Demers
    Correspondence
    Corresponding author: Clinical Chemistry and Core Endocrine Laboratory, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, Pennsylvania 17033
    Affiliations
    Professor of Pathology, Director, Clinical Chemistry and Core Endocrine Laboratory, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, Pennsylvania
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      Disturbances in prostaglandin synthesis and/or metabolism have been associated with the expression of multiple symptoms in various human disease states. Pain, fever, inflammation, and diarrhea are general symptoms among several that occur in patients who overproduce prostaglandins. Treatment of patients with prostaglandin-related symptoms in specific disease states can be achieved with prostaglandin synthesis inhibitor drugs. Plasma and urine measurements of prostaglandins can be of use in the diagnosis and monitoring of treatment of specific human diseases where prostaglandin excess is causative of the disease symptoms.
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