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Research Article| Volume 4, ISSUE 4, P729-744, December 1984

Assessment of Hormonal Disorders of Water Metabolism

  • Myron Miller
    Correspondence
    Corresponding author: VA Medical Center, 800 Irving Avenue, Syracuse, New York 13210
    Affiliations
    Professor of Medicine, SUNY Upstate Medical Center; Medical Service, VA Medical Center, Syracuse, New York
    Search for articles by this author
DOI:https://doi.org/10.1016/S0272-2712(18)30898-9
Assessment of Hormonal Disorders of Water Metabolism
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      The pathophysiology of clinical disorders of water regulation can be elucidated both by measurement of the antidiuretic hormone (ADH) in blood and urine through RIA and by tests that assess the release of ADH from the neurohypophysial system through its action on the kidney. These procedures are capable of making an accurate diagnosis of water-losing and water-retaining disorders. The functional tests (water deprivation, hypertonic saline infusion, comparison of simultaneous urine and serum osmolality and water loading) are simple, readily available, relatively inexpensive, and can obviate the need for direct measurement of AVP by RIA in evaluating most clinical disorders of water regulation.
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      Article info

      Footnotes

      Supported in part by VA Research funds and by Grant RR-229 from the General Research Centers Program of the Division of Research Resources, National Institutes of Health.

      Identification

      DOI: https://doi.org/10.1016/S0272-2712(18)30898-9

      Copyright

      © 1984 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

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