Advertisement
Research Article| Volume 5, ISSUE 3, P545-560, September 1985

The Detection of Streptococcal Antigens Using Monoclonal Antibodies

  • Mary Catherine Harris
    Correspondence
    Corresponding author: Division of Neonatology, The Children’s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, Pennsylvania 19104
    Affiliations
    Assistant Professor of Pediatrics, Division of Neonatology of the Hospital of the University of Pennsylvania and The Children’s Hospital of Philadelphia and the Department of Pediatrics of the University of Pennsylvania, Philadelphia, Pennsylvania
    Search for articles by this author
  • Richard A. Polin
    Affiliations
    Associate Professor of Pediatrics, Division of Neonatology of the University of Pennsylvania and The Children’s Hospital of Philadelphia and The Department of Pediatrics of the University of Pennsylvania, Philadelphia, Pennsylvania
    Search for articles by this author
DOI:https://doi.org/10.1016/S0272-2712(18)30859-X
The Detection of Streptococcal Antigens Using Monoclonal Antibodies
Previous ArticleMonoclonal Antibodies for Bacterial Identification and Taxonomy: 1985 and Beyond
Next ArticleUse of Monoclonal Antibodies in the Diagnosis and Epidemiologic Studies of Legionellosis
      This paper is only available as a PDF. To read, Please Download here.
      This article describes the diagnostic applications of anti-streptococcal monoclonal antibodies. The discussion centers on monoclonal antibodies against group B streptococcus; other antistreptococcal antibodies are considered in less detail.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.

      Subscribe:

      Subscribe to Clinics in Laboratory Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Register: Create an account
      Institutional Access: Sign in to ScienceDirect

      References

        • Ancona R.J.
        • Ferrieri P.
        • Williams P.O.
        Maternal factors that enhance the acquisition of group B streptococci by newborn infants.
        J. Med. Microbiol. 1980; 13: 273-280
        • Anthony B.F.
        • Okada D.M.
        • Hobel C.J.
        Epidemiology of group B streptococcus: Longitudinal observations during pregnancy.
        J. Infect. Dis. 1978; 173: 524-530
        • Anthony B.F.
        • Eisenstadt R.
        • Carter J.
        • et al.
        Genital and intestinal carriage of group B streptococci during pregnancy.
        J. Infect. Dis. 1976; 143: 761-766
        • Baker C.J.
        • Barrett F.F.
        • Gordon R.C.
        • et al.
        Suppurative meningitis due to streptococci of Lancefield group B: A study of 33 infants.
        J. Pediatr. 1973; 82: 724-729
        • Baker C.J.
        • Kasper D.L.
        Correlation of maternal antibody deficiency with susceptibility to neonatal group B streptococcal infection.
        N. Engl. T. Med. 1976; 294: 753-756
        • Baker C.J.
        Group B streptococcal infections in neonates.
        Pediatr. Rev. 1979; 1: 5-15
        • Baker C.J.
        • Edwards M.S.
        • Kasper D.L.
        Role of antibody to native type III capsular polysaccharide of group B streptococcus in infant infection.
        Pediatrics. 1981; 63: 544-549
        • Baker C.J.
        • Edwards M.S.
        Group B streptococcal infections.
        in: Remington J.S. Klein J.O. Infectious Diseases of the Fetus and Newborn Infant. W. B. Saunders Co., Philadelphia1983
        • Bevilacqua M.P.
        • Amrani D.
        • Mosesson M.W.
        • et al.
        Receptors for cold-insoluble globulin (plasma fibronectin) on human monocytes.
        J. Exp. Med. 1981; 153: 42-60
        • Blanc W.A.
        Pathways of fetal and early neonatal infection.
        J. Pediatr. 1961; 59: 473-496
        • Boyer K.M.
        • Gadzala C.A.
        • Kelly P.D.
        • et al.
        Selective intrapartum chemoprophylaxis of neonatal group B streptococcal early-onset disease III: Interruption of mother-to-infant transmission.
        J. Infect. Dis. 1983; 148: 810-816
        • Boyer K.M.
        • Papierniak C.K.
        Transplacental passage of IgG antibody to group B streptococcus.
        J. Pediatr. 1984; 104: 618-620
        • Briles D.E.
        • Forman C.
        • Hudak S.
        • et al.
        Antiphosphocholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae.
        J. Exp. Med. 1982; 156: 1177-1185
        • Christensen R.D.
        • Rothstein G.
        • Hill H.R.
        • et al.
        The effect of hybridoma antibody administration upon neutrophil kinetics during experimental type III group B streptococcal sepsis.
        Pediatr. Res. 1983; 17: 795-799
        • Christensen R.D.
        • Rothstein G.
        • Hill H.R.
        • et al.
        Treatment of experimental group B streptococcal infection with hybridoma antibody.
        Pediatr. Res. 1984; 18: 1093-1096
        • Edwards M.S.
        • Baker C.J.
        Prospective diagnosis of early-onset group B streptococcal infection by countercurrent-immunoelectrophoresis.
        J. Pediatr. 1979; 94: 286-298
        • Egan M.L.
        • Pritchard D.G.
        • Dillon H.C.
        • et al.
        Protection of mice from experimental infection with type III group B streptococcus using monoclonal antibodies.
        J. Exp. Med. 1983; 158: 1006-1011
        • Eickhoff T.C.
        • Klein J.O.
        • Daly A.L.
        • et al.
        Neonatal sepsis and other infections due to group B beta-hemolytic streptococci.
        N. Engl. J. Med. 1964; 271: 1221-1228
        • Feigin R.D.
        • Wong M.
        • Shackleford P.G.
        • et al.
        Countercurrent-immunoelectrophoresis of urine as well as of CSF and blood for diagnosis of bacterial meningitis.
        J. Pediatr. 1976; 89: 773-775
        • Franciosi R.A.
        • Knostman J.D.
        • Zimmerman R.A.
        Group B streptococcalneonatal and infant infections.
        J. Pediatr. 1973; 82: 707-718
        • Fry R.M.
        Fatal infections by hemolytic streptococcus group B.
        Lancet. 1938; 1: 199-201
        • Hall R.T.
        • Barnes W.
        • Krishnan L.
        • et al.
        Antibiotic treatment of parturient women colonized with group B streptococci.
        Am. J. Obstet. Gynecol. 1976; 124: 630-634
        • Harris M.C.
        • Douglas S.D.
        • Kolski G.B.
        • et al.
        Functional properties of anti-group B streptococcal monoclonal antibodies.
        Clin. Immunol. Immunopathol. 1982; 24: 342-350
        • Harris M.C.
        • Polin R.A.
        Neonatal septicemia.
        Pediatr. Clin. North Am. 1983; 30: 243-258
        • Hasty D.L.
        • Beachey E.H.
        • Simpson W.A.
        • et al.
        Hybridoma antibodies against protective and nonprotective antigenic determinants of a structurally defined polypeptide fragment of streptococcal M protein.
        J. Exp. Med. 1982; 155: 1010-1018
        • Hill H.R.
        • Shigeoka A.O.
        • Augustine N.H.
        • et al.
        Fibronectin enhances the opsonic and protective activity of monoclonal and polyclonal antibody against group B streptococci.
        J. Exp. Med. 1984; 159: 1618-1628
        • Insel R.A.
        • Gigliotti F.
        Monoclonal antibodies.
        Am. J. Dis. Child. 1983; 137: 69-76
        • Kohler G.
        • Milstein C.
        Continuous cultures of fused cells secreting antibody of predefined specificity.
        Nature. 1975; 256: 495-497
        • Lancefield R.C.
        • McCarty M.
        • Evely W.N.
        Multiple mouse protective antibodies directed against group B streptococci.
        J. Exp. Med. 1975; 142: 165-179
        • MacDonald S.W.
        • Manuel F.R.
        • Embil J.A.
        Localization of group B beta-hemolytic streptococci in the female urogenital tract.
        Am. J. Obstet. Gynecol. 1979; 133: 57-59
        • McDaniel L.
        • Scott G.
        • Kearney J.F.
        • et al.
        Monoclonal antibodies against protease sensitive pneumococcal antigens can protect mice from fatal infection with Streptococcus pneumoniae.
        J. Exp. Med. 1984; 160: 386-397
        • Morrow D.L.
        • Kline J.B.
        • Douglas S.D.
        • et al.
        Rapid detection of group B streptococcal antigen by monoclonal antibody sandwich enzyme assay.
        J. Clin. Microbiol. 1984; 19: 457-459
        • Nahm M.H.
        • Murray P.R.
        • Clevinger B.L.
        • et al.
        Improved diagnostic accuracy using monoclonal antibody to group A streptococcal carbohydrate.
        J. Clin. Microbiol. 1980; 12: 506-508
        • Nocard E.
        • Mollereau A.
        Sur une mammite contagieuse des raches laitieres.
        Ann. Inst. Pasteur (Paris). 1887; 1: 109-126
        • Nowinski R.C.
        • Tam M.R.
        • Goldstein L.C.
        • et al.
        Monoclonal antibodies for diagnosis of infectious diseases in humans.
        Science. 1983; 219: 637-644
        • Pass M.A.
        • Grey B.M.
        • Khare S.
        • et al.
        Prospective studies of group B streptococcal infections in infants.
        J. Pediatr. 1979; 95: 437-443
        • Polin R.A.
        • Kennett R.
        Use of monoclonal antibodies in an enzyme-linked inhibition assay for rapid detection of streptococcal antigen.
        J. Pediatr. 1980; 97: 540-544
        • Polin R.A.
        • Kennett R.
        Use of monoclonal antibodies in an enzyme immunoassay for rapid identification of group B streptococcus types II and III.
        J. Clin. Microbiol. 1980; 11: 332-336
        • Polin R.A.
        • Harris M.C.
        Monoclonal antibodies for bacterial infection.
        Clin. Immunol. Newslett., Am. Soc. Microbiol. 1983; 4: 153-158
        • Polin R.A.
        Monoclonal antibodies against microorganisms.
        Eur. J. Clin. Microbiol. 1984; 3: 387-398
        • Pyati S.P.
        • Pildes R.S.
        • Jacobs N.M.
        • et al.
        Penicillin in infants weighing two kilograms or less with early-onset group B streptococcal disease.
        N. Engl. J. Med. 1983; 303: 1383-1389
        • Schwaber J.F.
        • Posner M.R.
        • Schlossman S.F.
        • et al.
        Human-human hybrids secreting pneumococcal antibodies.
        Hum. Immunol. 1984; 9: 137-143
        • Shigeoka A.O.
        • Pineus S.H.
        • Rote N.S.
        • et al.
        Protective efficacy of hybridoma type specific antibody against experimental infection with group B streptococcus.
        J. Infect. Dis. 1984; 149: 363-372
        • Shigeoka A.O.
        • Jensen C.L.
        • Pineus S.H.
        • et al.
        Absolute requirement for complement in monoclonal IgM antibody-mediated protection against experimental infection with type III group B streptococci.
        J. Infect. Dis. 1984; 150: 63-70
        • Siegel J.D.
        • McCracken G.H.
        Detection of group B streptococcal antigens in body fluids of neonates.
        J. Pediatr. 1978; 93: 491-492
        • Siegel J.D.
        • McCracken G.H.
        • Threlkeld N.
        • et al.
        Single-dose penicillin prophylaxis against neonatal group B streptococcal infections.
        N. Engl. J. Med. 1980; 303: 769-775
        • Steigman A.J.
        • Bottone E.J.
        • Hanna B.A.
        Control of perinatal group B streptococcal sepsis: Efficacy of single injection of aqueous penicillin at birth.
        Mt. Sinai J. Med. 1978; 45: 685-693
        • Steinitz M.
        • Tamir S.
        • Goldfarb A.
        Human anti-pneumococci antibody produced by Epstein-Barr Virus (EBV) Immortalized Cell Line.
        J. Immunol. 1984; 132: 877-882
        • Thirumoorthi M.C.
        • Dajani A.S.
        Comparison of staphylococcal coagglutination, latex agglutination, and countercurrent-immunoelectrophoresis for bacterial antigen detection.
        J. Clin. Microbiol. 1979; 9: 28-32
        • Yother J.
        • Forman C.
        • Gray B.
        • et al.
        Protection of mice from infection with Streptococcus pneumoniae by anti-phosphocholine antibody.
        Infect. Immun. 1982; 36: 184-188
        • Yow M.D.
        • Mason E.O.
        • Leeds L.J.
        • et al.
        Ampicillin prevents intrapartum transmission of group B streptococcus.
        J.A.M.A. 1979; 241: 1245-1247
        • Yow M.D.
        • Leeds L.J.
        • Thompson P.K.
        • et al.
        The natural history of group B streptococcal colonization in the pregnant woman and her offspring: I. Colonization studies.
        Am. J. Obstet. Gynecol. 1980; 137: 34-38

      Article info

      Identification

      DOI: https://doi.org/10.1016/S0272-2712(18)30859-X

      Copyright

      © 1985 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

      ScienceDirect

      Access this article on ScienceDirect
      We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the for this site.
      Copyright © 2023 Elsevier Inc. except certain content provided by third parties. The content on this site is intended for healthcare professionals.


      RELX