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Research Article| Volume 5, ISSUE 3, P531-544, September 1985

Monoclonal Antibodies for Bacterial Identification and Taxonomy: 1985 and Beyond

DOI:https://doi.org/10.1016/S0272-2712(18)30858-8
Monoclonal Antibodies for Bacterial Identification and Taxonomy: 1985 and Beyond
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      Contemporary bacterial serology relevant to medicine involves poly- and monoclonal antibodies to study pathogenic bacteria and nonpathogenic organisms useful in controlling infectious diseases. Monoclonal antibody applications include immunodiagnostics, prophylaxis and serotherapy, and microbial biotechnology and molecular immunochemistry. If used in parallel with antisera, the analytic potential of monoclonal antibodies is better realized. However, the entire range of advantages from the use of monoclonal antibodies can only be attained if the antibodies are well characterized.
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      References

        • Balch W.E.
        • Fox G.E.
        • Magrum L.J.
        • et al.
        Methanogens: Re-evaluation of a unique biological group.
        Microbiol. Rev. 1979; 43: 260-296
        • Bergen T.
        Methods in Microbiology.
        Volume 15. Academic Press, London1984
        • Boulianne G.L.
        • Hozumi N.
        • Shulman M.J.
        Production of functional chimeraic mouse/human antibody.
        Nature. 1984; 312: 643-646
        • Brown S.L.
        • Bibb W.L.
        • McKinney R.M.
        Use of monoclonal antibodies in an epidemiological marker system: A retrospective study of lung specimens from the 1976 outbreak of Legionnaires disease in Philadelphia by indirect fluorescent-antibody and enzyme-linked immunosorbent assay methods.
        J. Clin. Microbiol. 1985; 21: 15-19
        • Cleveland W.L.
        • Wood I.
        • Erlanger B.F.
        Routine large-scale production of monoclonal antibodies in a protein-free culture medium.
        J. Immunol. Methods. 1983; 56: 221-234
        • Conway de Macario E.
        • Macario A.J.L.
        Long-term antibody synthesis in vitro: V. Conditions for prolonging the response, selection of different cell types, and interculture transfer of functional structures.
        Cell. Immunol. 1976; 25: 90-105
        • Conway de Macario E.
        • Macario A.J.L.
        Monoclonal antibodies for bacterial identification and taxonomy.
        A.S.M. News. 1983; 49: 1-7
        • Conway de Macario E.
        • Macario A.J.L.
        • Magarinos M.C.
        • et al.
        Dissecting the antigenic mosaic of the archaebacterium Methanobacterium thermoautotrophicum by monoclonal antibodies of defined molecular specificity.
        Proc. Natl. Acad. Sci. U.S.A. 1983; 80: 6346-6350
        • Dale J.B.
        • Beachey E.H.
        Unique and common protective epitopes among different serotypes of Group A streptococcal M proteins defined with hybridoma antibodies.
        Infect. Immun. 1984; 46: 267-269
        • DeFreitas E.C.
        • Vella S.
        • Linnenbach A.
        • et al.
        Human T-cell hybridomas with tetanus toxoidspecific helper activity.
        Curr. Topics Microbiol. Immunol. 1982; 100: 191-201
        • Edwards M.
        • McDade R.L.
        • Schoolnik G.
        • et al.
        Antigenic analysis of gonococcal pili using monoclonal antibodies.
        J. Exp. Med. 1984; 160: 1782-1791
        • Edwin C.
        • Tatini S.R.
        • Strobel R.S.
        • et al.
        Production of monoclonal antibodies to staphylococcal enterotoxin A.
        Appl. Environ. Microbiol. 1984; 48: 1171-1175
        • Haber E.
        Antibodies of restricted heterogeneity for structural study.
        Fed. Proc. 1970; 29: 66-71
        • Heckeis J.E.
        • Virji M.
        Monoclonal antibodies against gonococcal pili: Uses in the analysis of gonococcal imunochemistry and virulence.
        in: Macario A.J.L. Conway de Macario E. Monoclonal Antibodies Against Bacteria. Volume 1. Academic Press, Orlando1985
        • Hill H.R.
        • Shigeoka A.O.
        • Augustine N.H.
        • et al.
        Fibronectin enhances the opsonic and protective activity of monoclonal and polyclonal antibody against Group B streptococci.
        J. Exp. Med. 1984; 159: 1618-1628
        • Holmes N.J.
        • Parham P.
        Enhancement of monoclonal antibodies against HLA-A2 is due to antibody bivalency.
        J. Biol. Chem. 1983; 258: 1580-1586
        • Hunter K.W.
        Human monoclonal antibodies for prophylaxis and therapy of bacterial infections.
        in: Macario A.J.L. Conway de Macario E. Monoclonal Antibodies Against Bacteria. Volume 1. Academic Press, Orlando1985
        • Ivanyi J.
        • Krambovitis E.
        • Keen M.
        Evaluation of a monoclonal antibody (TB72)-based serological test for tuberculosis.
        Clin. Exp. Immunol. 1983; 54: 337-345
        • Jones S.A.
        • Marchitto K.S.
        • Miller J.N.
        • et al.
        Monoclonal antibody with hemagglutination, immobilization, and neutralization activities defines an immunodominant, 47,000 mol wt, surface-exposed immunogen of Treponema pallidum (Nichols).
        J. Exp. Med. 1984; 160: 1404-1420
        • Kaufmann S.H.E.
        Monoclonal T cells and T-cell hybridomas with antibacterial activity.
        in: Macario A.J.L. Conway de Macario E. Monoclonal Antibodies Against Bacteria. Volume 1. Academic Press, Orlando1985
        • Kohler G.
        • Milstein C.
        Continuous cultures of fused cells secreting antibody of predefined specificity.
        Nature. 1975; 256: 495-497
        • Kozbor D.
        • Roder J.
        Requirements for the establishment of high-titred human monoclonal antibodies against tetanus toxoid using the Epstein-Barr virus technique.
        J. Immunol. 1981; 127: 1275-1280
        • Krause R.M.
        The search for antibodies with molecular uniformity.
        Adv. Immunol. 1970; 12: 1-56
        • Lo M.M.S.
        • Tsong T.Y.
        • Conrad M.K.
        • et al.
        Monoclonal antibody production by receptor-mediated electrically induced cell fusion.
        Nature. 1984; 310: 792-794
        • Macario A.J.L.
        • Conway de Macario E.
        Low and high affinity antibodies can alternate during the immune response.
        Nature. 1973; 245: 263-264
        • Macario A.J.L.
        • Conway de Macario E.
        Cycling of long-term antibody responses in vitro: Before and after the hybridoma.
        in: Delisi C. Hiernaux J. Regulation of Immune Response Dynamics. Volume 2. CRC Press, Boca Raton1982
        • Macario A.J.L.
        • Conway de Macario E.
        Antibacterial monoclonal antibodies and the dawn of a new era in the control of infection.
        Surv. Synth. Pathol. Res. 1984; 3: 119-130
        • Macario A.J.L.
        • Conway de Macario E.
        A preview of the uses of monoclonal antibodies against methanogens in fermentation biotechnology: Significance for public health.
        in: Macario A.J.L. Conway de Macario E. Monoclonal Antibodies Against Bacteria. Volume 1. Academic Press, Orlando1985
        • Macario A.J.L.
        • Conway de Macario E.
        • Franceschi C.
        • et al.
        Attempt to separate antibody-forming clones of different affinity for one antigenic determinant on a macromolecule.
        in: Lindahl-Kiessling K. Alm G. Hanna Jr., M.G. Advances in Experimental Medicine and Biology. Volume 12. Plenum Press, New York1971
        • Margulies D.H.
        • Kuehl W.M.
        • Scharff M.D.
        Somatic cell hybridization of mouse myeloma cells.
        Cell. 1976; 3: 405-415
        • Meyer R.F.
        • Miller L.
        • Bennett R.W.
        • et al.
        Development of a monoclonal antibody capable of interacting with five serotypes of Staphylococcus aureus enterotoxin.
        Appl. Environ. Microbiol. 1984; 47: 283-287
        • Milstein C.
        • Cuello A.C.
        Hybrid hybridomas and their use in immunohistochemistry.
        Nature. 1983; 305: 537-540
        • Moyle W.R.
        • Lin C.
        • Corson R.L.
        • et al.
        Quantitative explanation for increased affinity shown by mixtures of monoclonal antibodies: Importance of a circular complex.
        Molec. Immunol. 1983; 20: 439-452
        • Norgard M.V.
        • Selland C.K.
        • Kettman J.R.
        • et al.
        Sensitivity and specificity of monoclonal antibodies directed against antigenic determinants of Treponema pallidum Nichols in the diagnosis of syphilis.
        J. Clin. Microbiol. 1984; 20: 711-717
        • Potter M.
        Immunoglobulin-producing tumors and myeloma proteins of mice.
        Physiol. Rev. 1972; 52: 631-719
        • Reading C.L.
        Theory and methods for immunization in culture and monoclonal antibody production.
        J. Immunol. Methods. 1982; 53: 261-291
        • Shigeoka A.O.
        • Jensen C.L.
        • Pincus S.H.
        • et al.
        Absolute requirement for complement in monoclonal IgM antibody-mediated protection against experimental infection with type III group B streptococci.
        J. Infect. Dis. 1984; 150: 63-70
        • Srikumaran S.
        • Guidry A.J.
        • Goldsby R.A.
        Bovine X mouse hybridomas that secrete bovine immunoglobulin Gl.
        Science. 1983; 220: 522-524
        • Taggart S.
        • Samloff I.M.
        Stable antibody-producing murine hybridomas.
        Science. 1982; 219: 1228-1230
        • Thompson N.E.
        • Ketterhagen M.J.
        • Bergdoll M.S.
        Monoclonal antibodies to staphylococcal enterotoxins B and C: Cross-reactivity and localization of epitopes on tryptic fragments.
        Infect. Immun. 1984; 45: 281-285
        • Tosi R.
        • Tanigaki N.
        • Sorrentino R.
        • et al.
        Binding of one monoclonal antibody to human la molecules can be enhanced by a second monoclonal antibody.
        Eur. J. Immunol. 1981; 11: 721-726
        • Volk W.A.
        • Bizzini B.
        • Snyder R.M.
        • et al.
        Neutralization of tetanus toxin by distinct monoclonal antibodies binding to multiple epitopes on the toxin molecule.
        Infect. Immun. 1984; 45: 604-609
        • Wilson G.
        • Miles A.
        • Parker M.T.
        Topley and Wilson’s Principles of Bacteriology, Virology, and Immunity. Volume 1: [Wilson, G., and Dick, H. M. (eds)]: General Microbiology and Immunity.
        Edition 7. The Williams & Wilkins Co., Baltimore1984
        • Zollinger W.D.
        • Mandrell R.E.
        Importance of complement source in bactericidal activity of human antibody and murine monoclonal antibody to meningococcal group polysaccharide.
        Infect. Immun. 1983; 401: 257-264
        • Zucker D.R.
        • Murphy J.R.
        Monoclonal antibody analysis of diphtheria toxin: I. Localization of epitopes and neutralization of cytotoxicity.
        Mol. Immunol. 1984; 21: 785-793
        • Zucker D.R.
        • Murphy J.R.
        • Pappenheimer Jr., A.M.
        Monoclonal antibody analysis of diphtheria toxin: II. Inhibition of ADP-ribosyl-transferase activity.
        Mol. Immunol. 1984; 21: 795-800

      Article info

      Footnotes

      Work done in the authors’ laboratories was supported by grants from the U.S. Department of Energy (DE-FG02-84ER 13197) and from the North Atlantic Treaty Organization (NATO No. 261.81/82).

      Identification

      DOI: https://doi.org/10.1016/S0272-2712(18)30858-8

      Copyright

      © 1985 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

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