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Research Article| Volume 6, ISSUE 3, P507-523, September 1986

Electrophoresis of Human Alkaline and Acid Phosphatases

  • Donald W. Moss
    Correspondence
    Corresponding Author: Hammersmith Hospital, Ducane Road, London W12 OHS, United Kingdom.
    Affiliations
    Professor of Clinical Enzymology, Royal Postgraduate Medical School (University of London), and Honorary Biochemist, Hammersmith Hospital, London, United Kingdom
    Search for articles by this author
DOI:https://doi.org/10.1016/S0272-2712(18)30796-0
Electrophoresis of Human Alkaline and Acid Phosphatases
Previous ArticleThe Clinical Use of Alkaline Phosphatase Enzymes
Next ArticleClinical Significance of Increased or Decreased Serum Alkaline Phosphatase Isoenzymes
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      Zone electrophoresis has played an important part in understanding the inter- and intratissue heterogeneity of acid and alkaline phosphatases. Electrophoresis of alkaline phosphatase in serum is of practical diagnostic value in deciding between liver and bone as alternative, or coexisting, sources of a raised total activity and, more rarely, in helping to define the contributions of other alkaline phosphatase isoenzymes. Certain tissue-specific patterns of acid phosphatase zones are also diagnostically useful in confirming the identity of isoenzymes in serum indicated by other techniques.
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      DOI: https://doi.org/10.1016/S0272-2712(18)30796-0

      Copyright

      © 1986 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

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