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Research Article| Volume 7, ISSUE 1, P199-248, March 1987

Electron Microscopy of Leukemias and Lymphomas

  • G. Richard Dickersin
    Correspondence
    Corresponding Author: Department of Pathology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02114.
    Affiliations
    Associate Professor, Department of Pathology, Harvard Medical School, and Head, Diagnostic Electron Microscopy Unit, The James Homer Wright Laboratories of the Massachusetts General Hospital, Boston, Massachusetts
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      The applications of electron microscopy in the study of leukemias and lymphomas are reviewed, with particular attention directed to the ultrastructural differences between lymphocytic and myelocytic leukemia, large-cell lymphoma and “undifferentiated” carcinoma, and smallcell lymphocytic lesions and other small round-cell neoplasms. Also covered are the importance of electron microscopy in the diagnosis of promyelocytic and megakaryocytic leukemia, and the unique ultrastructural features of hairy-cell leukemia, malignant histiocytosis, and histiocytosis X.
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