Research Article| Volume 7, ISSUE 3, P545-550, September 1987

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Lithium Monitoring

  • Christopher S. Frings
    Chris Frings Consulting Services, 633 Win wood Drive, Birmingham, Alabama 35226
    Senior Vice President, Technical Services, and Director, Clinical Chemistry and Toxicology, Medical Laboratory Associates

    Clinical Professor, Pathology Department, School of Medicine, and Clinical Professor, School of Community and Allied Health, University of Alabama, Birmingham, Alabama
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      Owing to a narrow therapeutic range and significant toxicides, lithium must be used with caution in the treatment of bipolar-effective illness. Blood samples for lithium monitoring should be obtained 12 hours after the evening dose. Clinicians should be aware of drug-drug interactions and make appropriate adjustments in lithium dosage whenever a change in regimen occurs.
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