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Research Article| Volume 7, ISSUE 3, P531-540, September 1987

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Chloramphenicol and Vancomycin

  • Joseph N. Miceli
    Correspondence
    Department of Pharmacology, The Morehouse School of Medicine, 720 Westview Drive, S. W. Atlanta, Georgia 30310
    Affiliations
    Professor, Department of Pharmacology and Medicine, The Morehouse School of Medicine, Atlanta, Georgia
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      These two antibiotics have been important agents in the treatment of serious infections. Chloramphenicol use is decreasing owing to the potentially fatal toxicities associated with its use. Vancomycin use, on the other hand, is increasing owing to the emergence of methicillin-resistant staphylococci. It is important to routinely monitor serum concentrations of these drugs. An overview of the pharmacology and methods of analysis for each drug is presented in this review.
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