Research Article| Volume 7, ISSUE 3, P513-529, September 1987

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Monitoring Aminoglycoside Therapy

  • Richard E. Mullins
    Corresponding author: Emory University Hospital, Clinical Chemistry Laboratory, Atlanta, Georgia 30322
    Assistant Professor, Department of Pathology and Laboratory Medicine, Emory University School of Medicine; Co-Director, Division of Clinical Chemistry, and Technical Director, Therapeutic Drug Monitoring Team, Emory University Hospital, Atlanta, Georgia
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  • Victor Lampasona
    Adjunct Associate Director, Mercer University Southern School of Pharmacy; Therapeutic Drug Monitoring Team Leader, and Director for Clinical and Educational Programs, Department of Pharmaceutical Services, Emory University Hospital, Atlanta, Georgia
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  • Rex B. Conn
    Professor and Vice Chairman, Department of Pathology and Cell Biology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania
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      The aminoglycoside antibiotics are indispensible therapeutic agents; however, a high incidence of toxic effects mandates that they be used with caution. Monitoring of serum aminoglycoside concentrations is essential in many types of patients, such as those having compromised renal function, those receiving a maximum dose of the drug, the obese, the elderly, and patients with cystic fibrosis.
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