Research Article| Volume 10, ISSUE 1, P215-236, March 1990

In Situ Hybridization

  • Mark H. Stoler
    Address reprint requests to: Mark H. Stoler, MD, Department of Pathology/L25, The Cleveland Clinic Foundation, One Clinic Center, 9500 Euclid Ave. Cleveland, OH 44195-5138
    Staff Pathologist, and Director, Molecular Biology Laboratory, Department of Pathology, The Cleveland Clinic Foundation, Cleveland, Ohio.
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      In situ hybridization is a technique with wide application in laboratory medicine. In this article, the basic and technical aspects of in situ hybridization are reviewed, and applications are discussed that emphasize methods for the detection of gene expression.
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