Advertisement
Research Article| Volume 10, ISSUE 1, P199-213, March 1990

Plastic Section Immunohistochemistry in the Diagnosis of Hematopoietic and Lymphoid Neoplasms

  • Author Footnotes
    * Assistant Professor
    Terence T. Casey
    Correspondence
    Address reprint requests to: Terence T. Casey, MD, Immunocytochemistry Laboratory, Department of Pathology, Vanderbilt University School of Medicine, Nashville, TN 37232-2561
    Footnotes
    * Assistant Professor
    Affiliations
    From the Immunocytochemistry Laboratory, Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee.
    Search for articles by this author
  • Author Footnotes
    † Technical Supervisor
    Sandra J. Olson
    Footnotes
    † Technical Supervisor
    Affiliations
    From the Immunocytochemistry Laboratory, Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee.
    Search for articles by this author
  • Author Footnotes
    ‡ Assistant Professor; Director of Laboratories, Vanderbilt University Hospital
    John B. Cousar
    Footnotes
    ‡ Assistant Professor; Director of Laboratories, Vanderbilt University Hospital
    Affiliations
    From the Immunocytochemistry Laboratory, Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee.
    Search for articles by this author
  • Author Footnotes
    § Professor
    Robert D. Collins
    Footnotes
    § Professor
    Affiliations
    From the Immunocytochemistry Laboratory, Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee.
    Search for articles by this author
  • Author Footnotes
    * Assistant Professor
    † Technical Supervisor
    ‡ Assistant Professor; Director of Laboratories, Vanderbilt University Hospital
    § Professor
      This paper is only available as a PDF. To read, Please Download here.
      Plastic section immunohistochemistry is presented as a useful alternative to conventional histologic and immunologic techniques in the diagnosis of hematopoietic and lymphoid neoplasms. The authors describe their experience with immunohistochemical assays on plastic-embedded tissues.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.

      Subscribe:

      Subscribe to Clinics in Laboratory Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Beckstead J.H.
        • Halverson P.S.
        • Ries C.A.
        • et al.
        Enzyme histochemistry of biopsy specimens of pathologic human bone marrow.
        Blood. 1981; 57: 1088-1097
        • Beckstead J.H.
        Optimal antigen localization in human tissues using aldehyde fixed plastic embedded sections.
        J Histochem Cytochem. 1985; 33: 954-958
        • Butler J.J.
        The Lukes-Butler classification of Hodgkin’s disease revisited.
        in: Bennett J.M. Controversies in the Management of Lymphomas. Martinus Nijhoff, Boston1983: 1-53
        • Casey T.T.
        • Cousar J.B.
        • Collins R.D.
        A simplified plastic embedding and immunohistologic technique for the immunophenotypic analysis of human hematopoietic and lymphoid tissues.
        Am J Pathol. 1988; 131: 183-189
        • Casey T.T.
        • Cousar J.B.
        • Collins R.D.
        Use of a simplified plastic embedding technique for immunophenotypic analysis of non-Hodgkin’s lymphomas.
        Lab Invest. 1988; 58: 17A
        • Casey T.T.
        • Olson S.J.
        • Cousar J.B.
        • et al.
        Immunophenotypes of Reed-Sternberg cells: A study of 19 cases of Hodgkin’s disease in plastic embedded sections.
        Blood. 1989; 74: 2624-2628
        • Casey T.T.
        • Olson S.J.
        • Glick A.G.
        • et al.
        Leukemias: Cytochemical and immunocyto-chemical analysis in plastic embedded tissue sections.
        Lab Invest. 1989; 60: 16A
        • Chan J.
        • Beckstead J.H.
        Leu-Ml antigen as a marker of acute non-lymphoid leukemia.
        Hematol Pathol. 1987; 1: 209-215
        • Chittal S.M.
        • Caveriviere P.
        • Schwarting R.
        • et al.
        Monoclonal antibodies in the diagnosis of Hodgkin’s disease: The search for a rational panel.
        Am J Surg Pathol. 1988; 12: 9-21
        • Falini B.
        • Stein H.
        • Pileri S.
        • et al.
        Expression of lymphoid associated antigens on Hodgkin’s and Reed-Sternberg cells of Hodgkin’s disease. An immunocytochemical study on lymph node cytospins using monoclonal antibodies.
        Histopathology. 1987; 11: 1229-1242
        • Foon K.A.
        • Todd R.F.
        Immunologic classification of leukemia and lymphoma.
        Blood. 1986; 68: 1-31
        • Glick A.D.
        • Collins R.D.
        Ultrastructural characterization of the Reed-Sternberg cell as a monocyte-macrophage: A commentary.
        Blood Cells. 1980; 6: 533-535
        • Kadin M.E.
        • Muramoto L.
        • Said J.
        Expression of T cell antigens in a. subset of patients with nodular sclerosing and mixed cellularity Hodgkin’s disease.
        Am J Pathol. 1988; 130: 345353
        • Li C.
        • Ziesmer S.C.
        • Lazcano-Villareal O.
        Use of azide and hydrogen peroxide as an inhibitor for endogenous peroxidase in the immunoperoxidas e method.
        J Histochem Cytochem. 1987; 35: 1457-1460
        • Lukes R.J.
        Criteria for involvement of lymph node, bone marrow, spleen, and liver in Hodgkin’s disease.
        Cancer Res. 1971; 31: 1755-1767
        • Macon W.R.
        • Casey T.T.
        • Greer J.P.
        • et al.
        Peripheral T cell lympho mas: A histopathologic and immunologic review of 102 cases.
        Lab Invest. 1989; 60: 56A
        • Mason D.Y.
        • Erber W.N.
        • Falini B.
        • et al.
        Immunoenzymatic labelling of haematological samples with monoclonal antibodies.
        in: Beverly P.C.L. Monoclonal Antibodies, Methods in Haematology. 13. Churchill Livingstone, London1986: 145-181
        • Picker L.J.
        • Weiss L.M.
        • Medeiros L.J.
        • et al.
        Immunophenotypic criteria for the diagnosis of non-Hodgkin’s lymphoma.
        Am J Pathol. 1987; 128: 181-201
        • Pincus G.S.
        • Said J.W.
        Hodgkin’s disease, lymphocyte predominance type, nodular—A distinct entity?.
        Am J Pathol. 1985; 118: 1-6
        • Ramsay A.D.
        • Smith W.J.
        • Isaacson P.G.
        T cell-rich B cell lymphoma.
        Am J Surg Pathol. 1988; 12: 433-443
        • Ruddell C.
        Hydroxyethyl methacrylate combined with polyethylene glycol 400 and water: An embedding medium for routine 1-2 micron sectioning.
        Stain Technol. 1967; 42: 119-123
        • Salhany K.E.
        • Cousar J.B.
        • Greer J.P.
        • et al.
        Transformation of cutaneous T cell lymphoma to large cell lymphoma: A clinicopathologic and immunologic study.
        Am J Pathol. 1988; 132: 265-277
        • Stein H.
        • Bonk A.
        • Tolksdorf G.
        • et al.
        Immunohistologic analysis of the organization of normal lymphoid tissue and non-Hodgkin’s lymphomas.
        J Histochem Cytochem. 1980; 28: 746-760
        • Stein H.
        • Mason D.Y.
        • Gerdes J.
        • et al.
        The expression of the Hodgldn’s disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: Evidence that Reed-Stern berg cells and histiocytic malignancies are derived from activated lymphoid cells.
        Blood. 1985; 66: 848-858
        • Sternberger L.A.
        Immunocytochemistry.
        3rd edition. John Wiley and Sons, New York1986: 90-200
        • Swerdlow S.H.
        • Wright S.A.
        The spectrum of Leu-Ml staining in lymphoid and hematopoietic proliferations.
        Am J Clin Pathol. 1986; 85: 283-288
        • Takamiya H.
        • Batsford S.
        • Vogt A.
        An approach to postembedding staining of protein (immunoglobulin) antigen embedded in plastic: Prerequisites and limitations.
        J Histochem Cytochem. 1980; 28: 1041-1049
        • Taylor C.R.
        Immunomicroscopy: A Diagnostic Tool for the Surgical Pathologist. W.B. Saunders Co, Philadelphia1986: 23-69
        • Timens W.
        • Visser L.
        • Poppema S.
        Nodular lymphocyte predominance of Hodgkin’s disease is a germinal center lymphoma.
        Lab Invest. 1986; 54: 457-461
        • Warnke R.
        • Levy R.
        Detection of T and B cell antigens with hybridoma monoclonal antibodies: A biotin-avidin-horseradish peroxidase method.
        J Histochem Cytochem. 1980; 28: 771-776
        • Weiss L.M.
        • Winter W.J.
        • Phyliky R.L.
        • et al.
        Peripheral T cell lymphomas: Histologic, immunohistologic, and clinical characterization.
        Mayo Clin Proc. 1986; 61: 411-412
        • Woodruff L.A.
        • Norris W.P.
        Sectioning of undecalcified bone.
        Stain Technol. 1955; 30: 179