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Research Article| Volume 10, ISSUE 1, P151-178, March 1990

Immunohistochemical Diagnosis of Nervous System Neoplasms

  • Suzanne M. de la Monte
    Correspondence
    Address reprint requests to: Suzanne M. de la Monte, MD, Department of Pathology, Warren 3, Massachusetts General Hospital, Fruit Street, Boston, MA 02114
    Affiliations
    Assistant Professor, Department of Pathology, Harvard Medical School; Charles S. Kubik Laboratory of Neuropathology, Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts.
    Search for articles by this author
DOI:https://doi.org/10.1016/S0272-2712(18)30586-9
Immunohistochemical Diagnosis of Nervous System Neoplasms
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      The last decade of literature pertaining to the immunohistochemical profiles of peripheral and central nervous system neoplasms is discussed. The survey includes a critical analysis of studies concerning peripheral nerve sheath tumors, granular cell tumors, meningiomas, hemangioblastomas, choroid plexus neoplasms, primary malignant lymphomas and their distinction from mononuclear inflammatory cell lesions, angioendotheliosis, astrocytomas, oligodendrogliomas, ependymomas, neuroblastomas, retinoblastomas, medulloblastomas, pineal cell tumors, neuroendocrine cell neoplasms, germ cell tumors, chordomas, and metastatic carcinomas. The panel of antibodies that should be used to draw diagnostic distinctions among similar-appearing or related tumors, and the expected results of immunohistochemical staining are summarized in tables for quick reference.
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      DOI: https://doi.org/10.1016/S0272-2712(18)30586-9

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      © 1990 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

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