Research Article| Volume 12, ISSUE 3, P587-602, September 1992

Hemapheresis in Pregnancy*

  • R. Ben Dawson
    Address reprint requests to: R. Ben Dawson, MD, Baltimore Rh Typing Laboratory, 400 W. Franklin Street, Baltimore, MD 21201
    From the University of Maryland School of Medicine; and the Therapeutic Apheresis Center, Baltimore Rh Typing Laboratory, Baltimore, Maryland
    Search for articles by this author
  • Author Footnotes
    * This article is dedicated to the memory of Isadore Siegel, MD, a founder of the Baltimore Rh Typing Laboratory in 1945, and to the prescient wisdom of Lois A. Bilenki, technologist and manager who for four decades inspired innovation and facilitated development and progress in the diagnosis and treatment of human disease in hematology, pregnancy, and transfusion medicine.
      This paper is only available as a PDF. To read, Please Download here.
      Hemapheresis, the removal of part of an individual’s blood with the remainder returned to the individual, is generally as safe in pregnant as in nonpregnant individuals. Three additional conditions, however, are of particular significance to the pregant patient: hemolytic disease of the newborn, increased maternal-fetal mortality in the patient with sickle cell disease; and thrombotic thrombocyopenic purpura and hemolytic uremic syndrome disorders. Topics include technology, plasma and blood volume calculations and considerations, and therapeutic hemapheresis.
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