Research Article| Volume 12, ISSUE 3, P577-586, September 1992

Neonatal Alloimmune Thrombocytopenia

  • Thomas S. Kickler
    Address correspondence to: Thomas S. Kickler, MD, The Johns Hopkins Hospital Blood Bank, Carnegie Building, Room 667, 600 N. Wolfe Street, Baltimore, MD 21205
    From The Johns Hopkins Hospital Blood Bank, The Johns Hopkins University School of Medicine, Baltimore, Maryland
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      Neonatal alloimmune thrombocytopenia is caused by the transplacental passage of maternal antibodies directed against platelet-specific antigens. Because complications from bleeding may result, prompt institution of therapy may be necessary. Accurate diagnosis by serologic techniques permits appropriate therapy to be administered both prenatally and postnatally.