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Research Article| Volume 12, ISSUE 4, P655-667, December 1992

Evolution in Indications for Blood Component Transfusion

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      The indications for blood component transfusion continue to evolve. The suggested hemoglobin level for red cell transfusion has been lowered from 10 to 7 g/dL with indices of oxygen delivery and consumption promoted for clinical decision making. More conservative criteria for platelet transfusion have been supported by new data, with levels of 5000/mm3 for the bleeding patient. Plasma and cryoprecipitate transfusion are based on the laboratory assays for coagulation combined with clinical bleeding or the requirement for an invasive procedure. Guidelines based on consensus are available but cannot replace careful correlation of clinical and laboratory assessment of the patient.
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