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Methodologic aspects including causes of factitious hyperphosphatemia and hypophosphatemia
are summarized. The differential diagnosis of hyperphosphatemia is reviewed under
its three broad causes: decreased glomerular filtration rate, increased exogenous
or endogenous phosphate load, and increased renal tubular phosphate reabsorption.
The differential diagnosis of hypophosphatemia is reviewed under its three broad causes:
inadequate gastrointestinal input, excess phosphate losses, and transcellular shifts.
The consequences of hyperphosphatemia and hypophosphatemia are outlined with a focus
on pathophysiologic and clinicochemical sequelae. A laboratory perspective is emphasized
in outlining management strategies.
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© 1993 Elsevier Inc. Published by Elsevier Inc. All rights reserved.