Research Article| Volume 13, ISSUE 1, P103-116, March 1993

Fundamentals of Clinical Acid-Base Evaluation

  • Harry G. Preuss
    Address reprint requests to: Harry G. Preuss, MD, Georgetown University Medical Center, Building D, Room G52B, 3800 Reservoir Road, NW, Washington, DC 20007.
    From the Nephrology Division, Department of Medicine, Georgetown University Medical Center, Washington, DC
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      The final diagnosis of acid-base perturbations relies on laboratory analyses. The major direct tools of assessment are arterial pH and PC02 and serum electrolytes. From these values, a diagnosis of metabolic acidosis, respiratory acidosis, metabolic alkalosis, and respiratory alkalosis with or without an excess anionic gap and with or without a proper compensatory response is made.