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Research Article| Volume 14, ISSUE 2, P423-444, June 1994

Lead Poisoning-Part I: Incidence, Etiology, and Toxicokinetics

DOI:https://doi.org/10.1016/S0272-2712(18)30386-X
Lead Poisoning-Part I: Incidence, Etiology, and Toxicokinetics
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      This article is, in essence, a collage of some recent and not so recent but lesser known information on lead poisoning. The article reviews the incidence of lead poisoning and the fact that no one is really safe from its effects. The sources of lead poisoning are also examined, as well as the ways in which lead enters the body and is eventually dealt with in the body.
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      References

        • Accardo P.
        • Whitman B.
        • Caul J.
        • et al.
        Autism and plumbism.
        Clinical Pediatrics. 1988; 27: 41-44

      2. Agency for Toxic Substances and Diseases Registry: The Nature and Extent of Lead Poisoning in Children in the United States: A report to Congress. Atlanta, GA, U.S. Department of Health and Human Services, Public Health Service, July 1988

      3. Agency for Toxic Substances and Disease Registry: Toxicological Profile for Lead. Prepared by Technical Resources Inc. Contract No. 68-03-3268, February 1988

        • Alcott J.V.
        • et al.
        Acute lead poisoning in two users of illicit methamphetamine.
        JAMA. 1987; 258: 510-511

      5. Alliance to end childhood lead poisoning: Final Summary of Federal legislation on lead poisoning prevention: 102nd Congress. October 1991. Washington, DC, Updated October 1992; 600 Pennsylvania Ave. S.E.; Suite 100

        • Angle C.R.
        • Huseman C.A.
        Childhood blood lead: Growth and neuroendocrine toxicity.
        Vet Hum Toxicol. 1989; 31: 341
        • Annest J.L.
        • Pirkle J.L.
        • Makuc D.
        • et al.
        Chronological Trend in Blood Lead levels between 1976 and 1980.
        N Engl J Med. 1983; 308: 1373-1377
        • Antonnini G.
        • Ferracuti S.
        • Pennisi E.
        • et al.
        Wine poisoning as a source of lead intoxication.
        Am J Med. 1989; 87: 238-239
        • Badiazadegan K.
        • Thompson K.M.
        Lead in infant formula (Letter).
        N Engl J Med. 1992; 326: 1361
        • Baghurst P.A.
        • Shi-Lu T.
        • McMichael A.J.
        • et al.
        Determinants of blood lead concentrations to age 5 years in a birth cohort study of children living in the lead smelting city of Port Pirie and surrounding areas.
        Arch Environ Health. 1992; 47: 203-210
        • Baker D.
        • Brender J.
        • Davis K.C.
        • et al.
        Cadmium and lead exposure associated with pharmaceutical imported from Asia—Texas.
        MMWR. 1989; 38: 612-614
        • Barry P.S.I.
        A comparison of concentrations of lead in human tissues.
        Br J Industr Med. 1975; 32: 119-139
        • Berwick D.M.
        • Komaroff A.L.
        Cost effectiveness of lead screening.
        N Engl J Med. 1982; 306: 1392-1398
        • Bell R.R.
        • Spickett J.T.
        The influence of milk in the diet on the toxicity of orally ingested lead in rats.
        Food Cosmet Toxicol. 1981; 19: 429-436
        • Bellinger D.
        • Levinton A.
        • Rabinovitz M.
        Correlates of low level lead exposure in urban children at 2 years of age.
        Pediatrics. 1986; 77: 826-833
        • Bellinger D.
        • Levinton A.
        • Waternaux C.
        • et al.
        Longitudinal analysis of prenatal and postnatal lead exposure and early cognitive development.
        N Engl J Med. 1987; 316: 1037-1043
        • Bois F.Y.
        • Tozer T.N.
        • Zeise L.
        Application of clearance concepts to the assessment of exposure to lead in drinking water.
        Am J Public Health. 1989; 79: 827-831

      18. Brelis M: 2 brain damaged by lead are awarded nearly $1.7 m. Boston Globe, April 23, 1993, p 25

        • Brown M.J.
        • Degiacomo J.M.
        • Gallagher G.
        • et al.
        Lead poisoning in children of different ages (Letter).
        N Engl J Med. 1990; 323: 135-136
        • Carton J.A.
        • Maradona J.A.
        • Arribas J.M.
        Acute—sub acute lead poisoning: Clinical findings and comparative study of diagnostic tests.
        Arch Intern Med. 1987; 147: 697-703

      21. Centers for Diseases Control: Strategic Plan for the Elimination of Childhood Lead Poisoning. Atlanta, GA, Department of Health and Human Services, February 1991

      22. Chamberlin AC, Heard MJ, Little P, et al: Investigations into lead from motor vehicles. Harwell, United Kingdom Atomic Energy Authority, Report No. AERE—R9198, 1978

        • Chandler D.B.
        • Norton R.L.
        • Kauffman K.W.
        • et al.
        Lead poisoning associated with intravenous methamphetamine use—Oregon 1988.
        MMWR. 1989; 38: 830-831
        • Charney E.
        • Kessler B.
        • Farfel M.
        • et al.
        Childhood lead poisoning: A controlled trial of the effect of dust control measures on blood lead levels.
        N Engl J Med. 1983; 309: 1089-1093
        • Clark M.
        • Royal J.
        • Seeler R.
        Interaction of iron deficiency and lead and the hematologic findings in children with severe lead poisoning.
        Pediatrics. 1988; 81: 247-254
        • Committee on Biologic Effects of Atmosphere Pollutants
        Lead: Airborne lead in perspective. National Academy of Science, Washington, DC1972
        • Committee on Environmental Hazards and Committee on Accident and Poison Prevention
        Statement on childhood lead poisoning.
        Paediatrics. 1987; 79: 457-465
        • Cooney G.H.
        • Mcbride W.
        • Bell A.
        • et al.
        Neurobehavioural consequences of prenatal low level exposure to lead.
        Neurotox Teratol. 1989; 11: 95-104
        • Cory-Slectha D.A.
        Aging alters the tissue distribution of lead.
        Toxicologist. 1987; 7: 77
        • Cullen M.R.
        • Robbins J.M.
        • Eskenazi B.
        Adult inorganic lead intoxication: Presentation of 31 new cases and a review of recent literature.
        Medicine (Baltimore). 1983; 62: 221-247
        • Current trends
        Childhood Lead Poisoning—United States: Report to the Congress by the Agency for Toxic Substances and Diseases Registry.
        MMWR. 1988; 37: 481-485
        • Dabeka R.W.
        Survey of lead, cadmium, cobalt and nickel in infant formulas and evaporated milks and estimation of dietary intakes of the elements by infants 0-12 months old.
        Sci Tot Environ. 1989; 89: 279-289
        • Daniel K.
        • Sellis M.H.
        • Polk L.
        • et al.
        Childhood lead poisoning New York City 1988.
        MMWR. 1990; 39: 1-7
        • Deinard A.S.
        • List A.
        • Lindgren B.
        • et al.
        Cognitive deficits in iron deficient and iron deficient anemic children.
        J Pediatr. 1986; 108: 681-689
        • Dietrich K.N.
        • Krafft K.M.
        • Bronschein R.L.
        • et al.
        Low level fetal lead exposure effect on neurobehavioural development in early infancy.
        Pediatrics. 1987; 80: 721-730
        • Emson H.E.
        For want of an heir: The obstetrical history of Queen Anne.
        Br Med J. 1992; 304: 1365-1366

      37. Environmental Protection Agency 1986: Air Quality Criteria for lead, June 1986; and addendum, Sept. 1986. Research Triangle Park, NC, Office of Research and Development, Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, EPA, EPA600/8-83-018F

        • Faust D.
        • Brown J.
        Moderately elevated blood lead levels: Effects on neurophysiologic functioning in children.
        Pediatrics. 1987; 80: 623-629

      39. Federal Register: Lead exposure in construction industry: Interim final rules. Federal Register; 1993; May 4; Dept, of Labor; OSHA; 29 CFR Part 1926

        • Feldman R.G.
        Urban Lead mining: Lead intoxication among deleaders.
        N Engl J Med. 1976; 298: 1143-1145
        • Fell G.S.
        Lead toxicity: Problems of definition and laboratory evaluation.
        Ann Clin Biochem. 1984; 21: 453-460
        • Figuero J.P.
        • Keenlyside R.A.
        Occupational and Environmental Lead Poisoning Associated with Battery Repair Shops—Jamaica.
        MMWR. 1989; 38: 474481
        • Fischbein A.
        Exposure to lead in firing ranges.
        JAMA. 1979; 241: 1141-1144
        • Flegal A.R.
        Lead levels in Preindustrial humans.
        N Engl J Med. 1992; 326: 1293-1294
        • Fruend E.
        • Seligman P.J.
        • Chorba T.L.
        • et al.
        Mandatory reporting of occupational diseases by clinicians.
        JAMA. 1989; 262: 3041-3044
        • From the Centers for Disease Control
        Lead Poisoning Associated with Intravenous Methamphetamine Use Oregon, 1988. Leads from the MMWR.
        JAMA. 1990; 236: 797-798
        • Fulton M.
        • Raab
        • Thompson G.
        Influence of blood lead on the ability and attainment of children in Edinburgh.
        Lancet. 1987; 1: 1221-1226
        • Gabriel H.F.
        • Goldblatt S.A.
        Lead Toxicity. Drug Monitoring and Toxicology No DM 91-3(DM-65). American Society of Clinical Pathologists, Chicago1991: 1-5
        • Garrettson L.K.
        Lead.
        in: Haddad L.M. Winchester J.F. Clinical Management of Poisoning and Overdose. ed 2. WB Saunders, Philadelphia1990: 649-655
        • Gerson B.
        Lead.
        Clin Lab Med. 1990; 10: 441-457
        • Glotzer D.E.
        • Bauchner H.
        Management of childhood lead poisoning: A survey.
        Pediatrics. 1992; 89: 614-618
        • Goldman R.H.
        • Baker E.L.
        • Hannan M.
        • et al.
        Lead poisoning in automobile radiator mechanics.
        N Engl J Med. 1987; 317: 214-218

      53. Goode EE: Putting the lid on dangerous dinnerware. US News and World Report, Aug 10, 1987, p 56

        • Goyer R.A.
        “Lead” in Toxic Effects of Metals.
        in: Klassen C.D. Amdur M.O. Doull J. Toxicology—Basic Science of Poisons. Macmillan, New York1986: 623-642
        • Graef J.W.
        • Shannon M.
        In reply to letter (92).
        Pediatrics. 1992; 90: 131-132
        • Grandjean P.
        • Holma B.
        A history of Lead Retention in the Danish Population.
        Environ Physiol Biochem. 1973; 3: 268-273
        • Grandjean P.
        • Jensen B.M.
        • Sando S.H.
        • et al.
        Delayed blood regeneration in lead exposure: An effect on reserve capacity.
        Am J Public Health. 1989; 79: 1385-1388
        • Grobler S.R.
        • Maresky L.S.
        • Kotze T.J.v.W.
        Lead reduction of petrol and blood lead concentrations of athletes.
        Arch Environ Health. 1992; 47: 139-142

      59. Grossfeld S: Life in the poison zones. Boston Sunday Globe, March 28, 1993 pp 1, 24-27

        • Graziano J.H.
        • Lolacono N.J.
        • Meyer P.
        Dose response study of oral 2, 3-dimercaptosuccinic acid in children with elevated blood lead concentrations.
        J Pediatr. 1988; 113: 751-757
        • Guthrie R.
        Prevention of poisoning in children—An issue for both developing and industrialised countries (Letter).
        Pediatrics. 1988; 82: 524-525
        • Harlan W.R.
        • Landis R.
        • Schmouder R.L.
        • et al.
        Blood lead and Blood Pressure: Relationship in the Adolescent and Adult US Population.
        JAMA. 1985; 253: 530-534
        • Himmelstein J.
        • Pransky G.
        • Morse D.
        • et al.
        Lead poisoning in bridge demolition workers in Mass.
        MMWR. 1989; 38: 687-694
        • Himmelstein J.
        • Wolfson M.
        • Pransky G.
        • et al.
        Lead poisoning in bridge demolition workers—Massachusetts (MMWR extract).
        JAMA. 1989; 262: 2369-2370
        • Houk V.H.
        • et al.
        Assessing lead exposure from drinking water (editorial).
        Am J Public Health. 1989; 79: 823-824
        • Hu H.
        Knowledge of diagnosis and reproductive history among survivors of childhood plumbism.
        Am J Public Health. 1991; 81: 1070-1072
        • Huseman C.A.
        • Varma M.
        • Angle C.R.
        Neuroendocrine effects of toxic and low blood lead levels in children.
        Pediatrics. 1992; 90: 186-189
        • Johnson D.
        • Houghton K.
        • Seigel C.
        • et al.
        Occupational and Paraoccupational Exposure to lead—Colorado.
        MMWR. 1989; 38: 338-345
        • Johnson D.
        • Seigel C.
        • Martyny J.
        • et al.
        Occupational and para occupational exposure to lead—Colorado.
        MMWR. 1989; 38: 339-345
        • Jones R.R.
        The continuing hazard of lead in drinking water.
        Lancet. 1989; 354: 669
        • Kikano G.E.
        • Stange K.C.
        Lead poisoning in a child after a gunshot injury.
        J Fam Pract. 1992; 34: 498-504
        • Landrigan P.J.
        • Baker E.L.
        • Himmelstein J.S.
        • et al.
        Exposure to lead from the Mystic River Bridge: The dilemma of deleading.
        N Engl J Med. 1982; 306: 673-676
        • Landrigan P.J.
        • Graef J.W.
        Pediatric lead poisoning in 1987: The silent epidemic continues.
        Paediatrics. 1987; 79: 582-583
        • Leads from MMWR
        Childhood Lead Poisoning—Report to Congress by Agency for Toxic Substances and Disease Registry.
        JAMA. 1988; 260: 1523-1533
        • Levine F.
        • Muenke M.
        VACTERL association with high prenatal lead exposure: Similarities to animal models of lead teratogenicity.
        Pediatrics. 1991; 87: 390-392
        • Linakis J.G.
        • Shannon M.W.
        Plumbism in the children of young professionals: Yuppie Lead.
        Vet Hum Toxicol. 1989; 31: 341
        • Litovitz T.
        • Manoguerra A.
        Comparison of Paediatric Poisoning Hazards: An analysis of 3.8 million exposure incidents.
        Pediatrics. 1992; 89: 999-1006
        • Lussenhop D.H.
        Lead exposure and radiator repair work.
        Am J Public Health. 1989; 79: 1558-1560
        • Mahaffey K.R.
        • Annest J.L.
        • Roberts J.
        • et al.
        National estimates of blood lead levels: United States, 1976-1980. Association with selected demographic and socioeconomic factors.
        N Engl J Med. 1982; 307: 573-579
        • Marcus A.H.
        The body burden of lead: Comparison of mathematical models for accumulation.
        Environ Res. 1979; 19: 79-90
        • Markovitz M.E.
        • Rosen J.F.
        Assessment of lead stores in children: Validation of an 8-hour CaNa2EDTA provocative test.
        J Pediatr. 1984; 104: 337
        • Markowitz M.E.
        • Weinberger H.L.
        Immobilization—Related lead toxicity in previously lead poisoned children.
        Paediatrics. 1990; 86: 455-457
        • McElvaine M.D.
        Prevalence of radiographic evidence of paint chip ingestion among children with moderate to severe lead poisoning, St. Louis, Missouri 1989-1990.
        Paediatrics. 1992; 89: 740-742
        • McMichael A.J.
        • Baghurst P.A.
        • Wigg N.R.
        • et al.
        Port Pirie Cohort study: Environmental exposure to lead and children’s abilities at the age of four years.
        N Engl J Med. 1988; 319: 468-475
        • Needleman H.L.
        Childhood lead poisoning: A disease for the history texts.
        Am J Public Health. 1991; 81: 685-687
        • Needleman H.L.
        • Davidson I.
        • Sewell E.M.
        • et al.
        Subclinical lead exposure in Philadelphia school children: Identification by dentine lead analysis.
        N Engl J Med. 1974; 290: 245-248
        • Needleman H.L.
        • Gastonis C.A.
        Low level exposure and the IQ of Children.
        JAMA. 1990; 263: 673-678
        • Needleman H.L.
        • Gunnoe C.
        • Levinton A.
        • et al.
        Deficits in psychologic and classroom performance of children with elevated dentine lead level.
        N Engl J Med. 1979; 300: 689-695
        • Needleman H.L.
        • Jackson R.J.
        Lead toxicity in the 21st century: Will we still be treating it?.
        Paediatrics. 1992; 89: 678-680
        • Needleman H.L.
        • Levinton A.
        Lead associated intellectual deficit (letter).
        N Engl J Med. 1982; 306: 367
        • Needleman H.L.
        • Schell A.
        • Bellinger D.
        • et al.
        The long term effects of exposure to low doses of lead in childhood: A 11 year follow up.
        N Engl J Med. 1990; 322: 83-88
        • Needleman H.L.
        • Shapiro I.M.
        Dentine lead levels in asymptomatic Philadelphia school children: Subclinical exposure in high and low risk groups.
        Environ Health Perspectives. 1974; 7: 27-31
        • Newman J.
        Would breast feeding decrease risks of lead intoxication? (Letter).
        Pediatrics. 1992; 90: 131

      94. New York State Joint Legislative commission on toxic substances and hazardous wastes: Lead Poisoning—Sources, Symptoms and Solutions. Albany, NY, January 1993

        • Nriagu J.O.
        Saturnine gout among Roman aristocrats: Did lead poisoning contribute to the fall of the Empire?.
        N Engl J Med. 1983; 308: 660-663

      96. Nuttall K: Evaluating lead exposure. Clinical Chemistry 32: ACP Check Sample 7/92, 1992

        • O’Connor M.E.
        CaEDTA vs CaEDTA plus BAL to treat children with elevated blood lead levels.
        Clin Pediatr. 1992; 31: 386-390
        • Pagliuca A.
        Lead Poisoning: An age old problem.
        Br Med J. 1990; 300: 830
        • Peitzman S.J.
        • Bodison W.
        • Ellis I.
        Moonshine drinking among hypertensive veterans in Philadelphia.
        Arch Intern Med. 1985; 145: 632-634
        • Perrota D.M.
        Surveillance of children’s blood lead levels—United States 1991; MMWR extract.
        JAMA. 1992; 268: 1654
        • Phil R.O.
        • Parkers M.
        Hair element content in learning disabled children.
        Science. 1977; 198: 204-206
        • Piomelli S.
        • Corash L.
        • Corash M.B.
        • et al.
        Blood lead concentrations in a remote Himalayan population.
        Science. 1980; 210: 1135-1137
        • Piomelli S.
        • Rosen J.F.
        • Chisolm J.J.
        • et al.
        Management of childhood lead poisoning.
        J Paediatr. 1984; 105: 523-532

      104. Centers for Disease Control: Preventing Lead Poisoning in young Children. Washington, DC, January 1985

        • Rabin R.
        Warnings Unheeded: A History of Child Lead Poisoning.
        Am J Public Health. 1989; 79: 1668-1674

      106. Rabin R, Davis L, Brooks D: Lead at work: Elevated blood lead levels in Massachusetts Workers; April-October 1991. Boston, MA, Department of Labor & Department of Public Health Mass. Publication, Aug. 1992

        • Rabinowitz M.B.
        • Wang J-D
        • Soong W-T
        Dentine lead and child intelligence in Taiwan.
        Arch Environ Health. 1991; 46: 351-360
        • Rabinovitz M.B.
        • Needleman H.L.
        Temporal trends in the lead concentrations of umbilical cord blood.
        Science. 1982; 216: 1429-1431
        • Racitti K.A.
        • Haloukas G.
        • Curran A.S.
        • et al.
        Lead poisoning following ingestion of homemade beverage stored in a ceramic jug—New York.
        MMWR. 1989; 38: 379-380
        • Ratcliffe J.M.
        Lead in man and the environment. Ellis Horwood Ltd., Chichester, UK1981
        • Rempel D.
        The Lead Exposed Worker.
        JAMA. 1989; 262: 532-534
        • Request for Assistance in Preventing Lead Poisoning in Construction Workers
        NIOSH—CDC ALERT; Extract from MMWR.
        JAMA. 1992; 267: 2012

      113. Request for assistance in preventing lead poisoning in construction workers. Washington, DC, National Institute for Occupational Safety and Health Public Health Service-CDC, April 1992

        • Rolls R.
        Obstetrical history of Queen Anne (letter).
        Br Med J. 1992; 304: 1572

      115. Roper WL: Preventing Lead Poisoning in Young Children. Centers for Disease Control. Washington, DC, October 1991

        • Rosen J.F.
        • Chesney R.W.
        • Hamstra A.
        • et al.
        Reduction in 1, 25-Dihydroxy vitamin D in children with increased lead absorption.
        N Engl J Med. 1980; 302: 1128-1131
        • Rosen J.F.
        • Markowitz M.E.
        • Bijur P.E.
        • et al.
        L x-ray fluorescence of cortical bone lead compared with the Ca2Na2 EDTA test in lead-toxic children. Public Health implications.
        Proc Natl Acad Sci (USA). 1989; 86: 685-689

      118. Royce SE, Needleman HL: Case Study in Environmental Medicine: Lead Toxicity. Toxic Substances and Disease Registry, June 1990

        • Rudolph L.
        • Maizlish N.
        • Tepper A.
        • et al.
        Surveillance for Occupational Lead Exposure-United States 1987.
        JAMA. 1989; 262: 2370-2372
        • Ruff H.A.
        • Bijur P.E.
        • Markowitz M.
        • et al.
        Declining blood lead levels and cognitive changes in moderately lead poisoned children.
        JAMA. 1993; 269: 1641-1646
        • Settle D.M.
        • Patterson C.C.
        Lead in albacore: Guide to lead pollution in America.
        Science. 1980; 207: 1167
        • Schwartz J.
        • Angle C.
        • Pitcher H.
        Relationship between childhood blood lead levels and stature.
        Pediatrics. 1986; 77: 281-288
        • Schwartz J.
        • Landrigan P.J.
        • Baker E.L.
        • et al.
        Lead induced anemia: Dose response relationship and evidence for a threshold.
        Am J Public Health. 1990; 80: 165-168
        • Schwartz J.
        • Landrigan P.J.
        • Feldman R.G.
        • et al.
        Threshold effect in lead induced peripheral neuropathy.
        J Paediatr. 1988; 112: 12-17
        • Schoen E.J.
        Lead toxicity in the 21st century: Will we be still treating it? (Letter).
        Pediatrics. 1992; 90: 481
        • Schroeder H.A.
        • Tipton I.H.
        The Human Body Burden of Lead.
        Arch Environ Health. 1968; 17: 965-978
        • Shaltout A.
        • Yaish S.A.
        • Fernando N.
        Lead encephalopathy in infants in Kuwait.
        Annals of Tropical Paediatrics. 1981; 1: 209-215
        • Shannon M.
        • Grace A.
        • Graef J.W.
        Use of penicillamine in children with small lead burdens (letter).
        N Engl J Med. 1989; 321: 979-980
        • Shannon M.W.
        • Graef J.W.
        Lead intoxication from water used to reconstitute infant formula.
        Clin Pediar. 1989; 28: 380-382
        • Shannon M.W.
        • Graef J.W.
        Lead intoxication in infancy.
        Paediatrics. 1992; 89: 87-90
        • Shannon M.W.
        • Graef J.
        Hazards of lead in infant formula (letter).
        N Engl J Med. 1992; 326: 137
        • Shannon M.W.
        • Graef J.W.
        Lead in infant formula; Letter in reply to Badizadegan K. & Thompson K.M.
        N Engl J Med. 1992; 326: 1361-1362
        • Shukla R.
        • Bornschein R.L.
        • Dietrich K.N.
        • et al.
        Fetal and infant lead exposure: Effects on growth in stature.
        Pediatrics. 1989; 84: 604-612
        • Shukla R.
        • Dietrich K.N.
        • Bronschein R.L.
        • et al.
        Lead exposure and growth in the early preschool child: A follow-up report from the Cincinnati lead study.
        Pediatrics. 1991; 88: 886-892
        • Silbergeld E.K.
        Lead in bone: Implications for toxicology during pregnancy and lactation.
        Environ Health Perspect. 1991; 91: 63-70
        • Stang H.J.
        • Nordin J.D.
        ZEP Screening for Iron Deficiency and Lead Poisoning.
        HMO Practice. 1988; 3: 109-113
        • Tackett S.L.
        Lead in the Environment: Effects of human exposure.
        APCR May. 1987; 17: 14-19
        • Thatcher R.W.
        • Lester M.L.
        • McAlaster R.
        • et al.
        Effects of low levels of cadmium and lead on cognitive functioning in children.
        Arch Environ Health. 1982; 37: 159-165
        • Thatcher R.W.
        • Lester M.L.
        • McAlaster R.
        • et al.
        Intelligence and lead toxins in rural children.
        J Learn Disabil. 1983; 16: 355-359
        • Tripathi R.K.
        • Sheretz P.C.
        • Llewellyn G.C.
        • et al.
        Lead exposure in outdoor firearm instructors.
        Am J Public Health. 1991; 81: 753-755
        • Valway S.E.
        • Martyny J.W.
        • Miller J.R.
        • et al.
        Lead absorption in indoor firing range users.
        Am J Public Health. 1989; 79: 1029-1032
        • Vance M.V.
        • Curry S.C.
        • Bradley J.M.
        • et al.
        Acute lead poisoning in nursing homes and psychiatric patients from the ingestion of lead-based ceramic glazes.
        Arch Intern Med. 1990; 150: 2085-2092
        • Weisel C.
        • Demak M.
        • Marcus A.H.
        • et al.
        Soft plastic bread packaging: Lead content and reuse by families.
        Am J Public Health. 1991; 81: 756-758
        • Wiley J.F.
        • Henretig F.M.
        • Selbst S.M.
        Blood lead levels in children with foreign bodies.
        Pediatrics. 1992; 89: 593-596
        • Wittmers L.E.
        • Wallgren J.
        • Alich A.
        • et al.
        Lead in Bone (IV). Distribution of lead in the human skeleton.
        Arch Environ Health. 1988; 43: 381-391
        • Yassi A.
        • Cheang M.
        • Tenenbein M.
        • et al.
        An analysis of occupational blood lead trends in Manitoba, 1979 through 1987.
        Am J Public Health. 1991; 81: 736-740

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      DOI: https://doi.org/10.1016/S0272-2712(18)30386-X

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      © 1994 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

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