Research Article| Volume 16, ISSUE 2, P395-406, June 1996

Hepatitis B and C Viruses and Hepatocellular Carcinoma

  • Michael C. Kew
    Address reprint requests to: Michael C. Kew, PhD, MD, DSc, FRCP, Department of Medicine, Witwatersrand University Medical School, 7 York Road, Parktown 2193, Johannesburg, South Africa
    From the Medical Research Council /University Molecular Hepatology Research Unit, Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa
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      This article focuses on probable mechanisms of hepatitis B virus- and hepatitis C virus-induced hepatocellular carcinoma and includes a discussion on whether the two viruses interact in hepato-cellular carcinogenesis. Possible interactions between these viruses and alcohol abuse in tumor development are considered as well. Although substantial progress has been made in understanding the cause and pathogenesis of hepatocellular carcinoma, much remains to be learned.
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