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Oxidized LDL, not the native LDL, promotes atherosclerosis. However, ox-LDL is usually
undetectable in the blood circulation. Autoantibodies against ox-LDL (γ ox-LDL), on
the other hand, are not only measurable in the blood but may also reflect the extent
of in vivo oxidation of native LDL and provide any early sign of risk for atherosclerosis.
Current assay for 7 ox-LDL needs improvement. Routine clinical application of this
assay has to wait until all parameters of this assay are defined and characterized.
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© 1997 Elsevier Inc. Published by Elsevier Inc. All rights reserved.