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Research Article| Volume 17, ISSUE 3, P547-558, September 1997

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Cytokines in Autoimmune Disease

  • Jeffrey S. Warren
    Correspondence
    Address reprint requests to Jeffrey S. Warren, MD, Department of Pathology, University of Michigan Medical School, 1301 Catherine Road, Ann Arbor, MI 48109-0602
    Affiliations
    From the Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan
    Search for articles by this author
DOI:https://doi.org/10.1016/S0272-2712(18)30209-9
Cytokines in Autoimmune Disease
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      Cytokines are peptide hormones that regulate a wide variety of immune and inflammatory processes. Individual cytokines are produced by many different cell types and exhibit pronounced pleiotropism. Cytokines such as tumor necrosis factor a interleukins -5, -10, and -12 play important roles in immunity. Interleukins -2 and -4, and transforming growth factor 7 mediate lymphocyte activation and differentiation.
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      DOI: https://doi.org/10.1016/S0272-2712(18)30209-9

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      © 1997 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

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