Research Article| Volume 17, ISSUE 4, P727-735, December 1997

Why Cardiospecificity is Preeminent in Myocardial Markers of Injury

  • Joseph H. Keffer
    Address reprint requests to Joseph H. Keffer, MD, Chief Medical Officer and Vice President, Spectral Diagnostics, Inc., 135-2 The West Mall, Toronto, Ontario M9C 1C2 Canada
    From Spectral Diagnostics, Inc., Toronto, Ontario, Canada
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      The most critical facet of a biochemical marker of ischemic heart disease is cardiospecificity. This flows from the fact that symptoms and alternative objective studies including coronary arteriography and electrocardiography are frequently insensitive in detecting coronary artery disease. The timely appearance of biochemical evidence of myocyte necrosis firmly asserts the presence of life threatening multi-focal coronary atherosclerosis which is often not otherwise knowable. Compliance in the response of physician and patient clearly depend on the perception of persuasive biochemical testimony.
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