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Research Article| Volume 18, ISSUE 1, P39-64, March 1998

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Traumatic Neuropathology

  • Gary S. Pearl
    Correspondence
    Address reprint requests to Gary S. Pearl, MD, PhD, Department of Pathology, Orlando Regional Medical Center, 1414 S. Orange Ave., Orlando, FL 32806
    Affiliations
    From the Department of Pathology, Orlando Regional Healthcare System; and the District IX Medical Examiner, Orlando, Florida
    Search for articles by this author
DOI:https://doi.org/10.1016/S0272-2712(18)30178-1
Traumatic Neuropathology
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      The neuropathology of trauma is reviewed based on the mechanism of injury. Pathology is divided into primary and secondary injury, based on the relationship to the time of injury. It is further divided by mechanism, with primary impact injury including skull fracture, epidural hematoma, brain contusion and laceration, and intracerebral hemorrhage; primary inertial injury including subdural hematoma, diffuse axonal injury, and diffuse vascular injury; and secondary injury including hypoxia/ischemia, brain swelling, infection, and increased intracranial pressure. The neuropathology of child abuse is also reviewed.
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      DOI: https://doi.org/10.1016/S0272-2712(18)30178-1

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