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Research Article| Volume 19, ISSUE 1, P169-186, March 1999

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Acute Lymphoblastic Leukemia

  • Steven J. Melnick
    Correspondence
    Address reprint requests to: Steven J. Melnick, PhD, MD, Department of Pathology, Miami Children’s Hospital, 3100 S.W. 62nd Avenue, Miami, FL 33155.
    Affiliations
    From the Department of Pathology and Laboratories, Miami Children’s Hospital, Miami, Florida
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      This paper is only available as a PDF. To read, Please Download here.
      This article reviews the laboratory methodologies used to evaluate acute lymphoblastic leukemia (ALL) in children and their role in establishing a diagnosis and prognosis of this disease. These methodologies are: morphology, flow cytometry, cytogenetics, and molecular diagnostics. Additionally, immunophenotypic classifications of ALL and criteria for establishing a diagnosis of ALL independent of morphology are described.
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