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Research Article| Volume 19, ISSUE 1, P39-70, March 1999

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The Influence of Developmental Haemostasis on the Laboratory Diagnosis and Management of Haemostatic Disorders During Infancy and Childhood

DOI:https://doi.org/10.1016/S0272-2712(18)30128-8
The Influence of Developmental Haemostasis on the Laboratory Diagnosis and Management of Haemostatic Disorders During Infancy and Childhood
Previous ArticleHematologic Values and Appearances in the Healthy Fetus, Neonate, and Child
Next ArticleQuantitative and Qualitative Platelet Disorders
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      The physiology of the hemostatic system in children is different from that in adults. Reference ranges for components of the hemostatic system are age dependent. During early childhood, physiologic values may overlap with values observed in congenital deficiencies of acquired pathological conditions. Physiologically decreased plasma concentrations of hemostatic components also influence the response to antithrombotic therapy. The relevance of developmental hemostasis for the laboratory diagnosis and management of hemorrhagic and thrombotic disorders during childhood is discussed.
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      DOI: https://doi.org/10.1016/S0272-2712(18)30128-8

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      © 1999 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

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