Research Article| Volume 20, ISSUE 2, P407-422, June 2000

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Treatment of Human Papillomavirus Gynecologic Infections

  • Karen J. Auborn
    Address reprint requests to: Karen J. Auborn, PhD, HPV Laboratory, Boas-Mark Biomedical Science Research Center, 350 Community Drive, Manhasset, NY 11030
    From the Department of Otolaryngology, Division of Research, Long Island Jewish Medical Center, New Hyde Park, New York

    The Long Island Campus of Albert Einstein College of Medicine, New Hyde Park, New York
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  • Timothy H. Carter
    Department of Biological Sciences, St. John’s University, Jamaica, New York
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      This paper is only available as a PDF. To read, Please Download here.
      HPV causes a continuum of pathologies ranging from subclinical infection to visible condylomas and is even a cofactor for cervical cancer and other cancers of the female genital tract. Routine gynecologic examination and the advent of simple screening procedures for cervical dysplasia and cancer have decreased the impact of HPV disease among many women; however, cervical cancer remains a serious health problem in less economically developed regions, and genital warts are one of the most widespread STDs among all women. Furthermore, current treatments fail to eliminate the underlying viral infection, leading to the possibility of recurrent disease. We review the biology and epidemiology of HPV, discuss current treatment modalities, and summarize research on promising new avenues of prevention and therapy.
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