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Research Article| Volume 20, ISSUE 3, P527-548, September 2000

The Genetics of Osteoporosis: Future Diagnostic Possibilities

DOI:https://doi.org/10.1016/S0272-2712(18)30051-9
The Genetics of Osteoporosis: Future Diagnostic Possibilities
Previous ArticleRisk Assessment for Osteoporosis II: Biochemical Markers of Bone Turnover: Bone Resorption Indices
Next ArticleSex Steroids and Osteoporosis: The Role of Estrogens and Androgens
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      The risk of developing osteoporosis is determined by the interaction of several mostly unknown genes and environmental factors. Genetic studies in osteoporosis have largely focussed on association studies of a small number of candidate genes, with few linkage studies performed, and large areas of the genome remaining unexplored. Identifying the genes involved in osteoporosis would be a major advance in our understanding of the causation of the disease, and lead to advances in diagnosis, risk prediction, and potentially preventive and therapeutic measures.
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      Article info

      Footnotes

      This work was supported in part by the Arthritis Research Campaign, Oliver Bird Fund (Nuffield Foundation), Medical Research Council (United Kingdom) (MAB) and the National Health and Medical Research Council of Australia, National Institutes of Health (USA), Aza Limited, Australian Kidney Foundation, Hoechst Marion Roussel, Merck Sharp and Dohme, Roche Australasia Ltd. (JAE).

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      DOI: https://doi.org/10.1016/S0272-2712(18)30051-9

      Copyright

      © 2000 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

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