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Research Article| Volume 21, ISSUE 3, P607-618, September 2001

Bioregulators as Instruments of Terror

  • Elliott Kagan
    Correspondence
    Address reprint requests to Elliott Kagan, MD, FRCPath, Department of Pathology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814-4799.
    Affiliations
    From the Department of Pathology, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland
    Search for articles by this author
DOI:https://doi.org/10.1016/S0272-2712(18)30024-6
Bioregulators as Instruments of Terror
Previous ArticleToxins as Weapons of Mass Destruction: A Comparison and Contrast With Biological-Warfare and Chemical-Warfare Agents
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      This paper is only available as a PDF. To read, Please Download here.
      Bioregulators are naturally occurring organic compounds that regulate diverse cellular processes. Unlike traditional diseasecausing biowarfare agents that take hours or days to act, many bioregulators act within minutes of administration. If exploited for the purpose of bioterrorism, they could potentially cause profound physiologic effects. Other effects may be more subtle. The main groups of bioregulators discussed are cytokines, eicosanoids, neurotransmitters, hormones, and proteolytic enzymes. Because advances continually are being made in their development, bioregulators should be considered as weapons with increasing bioterrorism potential.
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      Article info

      Footnotes

      This work was supported by research grants No. MDA905-01-1-0001 from the US Department of Defense and No. HL-54196 from the National Institutes of Health.

      Identification

      DOI: https://doi.org/10.1016/S0272-2712(18)30024-6

      Copyright

      © 2001 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

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