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- Morphine glucuronidation and glucosidation represent complementary metabolic pathways that are both catalyzed by UDP-glucuronosyltransferase 2B7: kinetic, inhibition, and molecular modeling studies.J Pharmacol Exp Ther. 2014; 349: 126-137
- Pharmacogenomics of cytochrome P450 3A4: recent progress toward the “Missing Heritability” problem.Front Genet. 2013; 4: 12
- Association between blood carisoprodol:meprobamate concentration ratios and CYP2C19 genotype in carisoprodol-drugged drivers: decreased metabolic capacity in heterozygous CYP2C19*1/CYP2C19*2 subjects?.Pharmacogenetics. 2003; 13: 383-388
- Association between CYP2C19 polymorphism and depressive symptoms.Am J Med Genet B Neuropsychiatr Genet. 2010; 153B: 1160-1166
- Toxicogenetics–cytochrome P450 microarray analysis in forensic cases focusing on morphine/codeine and diazepam.Int J Legal Med. 2013; 127: 395-404
- Clinical pharmacogenetics implementation consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype.Clin Pharmacol Ther. 2012; 91: 321-326
- Clinical pharmacogenetics implementation consortium guidelines for cytochrome P450 2D6 genotype and codeine therapy: 2014 update.Clin Pharmacol Ther. 2014; 95: 376-382
- Apnea and oxygen desaturations in children treated with opioids after adenotonsillectomy for obstructive sleep apnea syndrome: a prospective pilot study.Paediatr Drugs. 2012; 14: 411-415
- Urinary hydrocodone and metabolite distributions in pain patients.J Anal Toxicol. 2014; 38: 404-409
- Observations on hydrocodone and its metabolites in oral fluid specimens of the pain population: comparison with urine.J Opioid Manag. 2014; 10: 177-186
- Prescription opioids. IV: disposition of hydrocodone in oral fluid and blood following single-dose administration.J Anal Toxicol. 2015; 39: 510-518
- Metabolism and disposition of prescription opioids: a Review.Forensic Sci Rev. 2015; 27: 115-145
- Prescription opioids. II. Metabolism and excretion patterns of hydrocodone in urine following controlled single-dose administration.J Anal Toxicol. 2013; 37: 486-494
- Effects of paroxetine, a CYP2D6 inhibitor, on the pharmacokinetic properties of hydrocodone after coadministration with a single-entity, once-daily, extended-release hydrocodone tablet.Clin Ther. 2015; 37: 2286-2296
- The metabolism of opioid agents and the clinical impact of their active metabolites.Clin J Pain. 2011; 27: 824-838
- Prescription opioids. III. Disposition of oxycodone in oral fluid and blood following controlled single-dose administration.J Anal Toxicol. 2015; 39: 192-202
- Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: role of circulating active metabolites.Clin Pharmacol Ther. 2006; 79: 461-479
- Determination of oxycodone, noroxycodone and oxymorphone by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry in human matrices: in vivo and in vitro applications.J Anal Toxicol. 2013; 37: 337-344
- Prescription opioids. I. Metabolism and excretion patterns of oxycodone in urine following controlled single dose administration.J Anal Toxicol. 2013; 37: 255-264
- Exposure to oral oxycodone is increased by concomitant inhibition of CYP2D6 and 3A4 pathways, but not by inhibition of CYP2D6 alone.Br J Clin Pharmacol. 2010; 70: 78-87
- Evaluating the relationship of methadone concentrations and EDDP formation in chronic pain patients.J Anal Toxicol. 2012; 36: 239-249
- Evaluating the relationship of methadone concentrations and EDDP formation in chronic pain patients.J Anal Toxicol. 2012; 36: 239-249
- Methadone enantiomer plasma levels, CYP2B6, CYP2C19, and CYP2C9 genotypes, and response to treatment.Clin Pharmacol Ther. 2005; 78: 593-604
- CYP2B6 SNPs are associated with methadone dose required for effective treatment of opioid addiction.Addict Biol. 2013; 18: 709-716
- Methadone dose in heroin-dependent patients: role of clinical factors, comedications, genetic polymorphisms and enzyme activity.Br J Clin Pharmacol. 2015; 79: 967-977
- Glucuronidation of buprenorphine and norbuprenorphine by human liver microsomes and UDP-glucuronosyltransferases.Drug Metab Lett. 2009; 3: 101-107
- A Survey of ASAM Members’ knowledge, attitudes, and practices in urine drug testing.J Addict Med. 2015; 9: 399-404
- Urine drug testing of chronic pain patients. III. Normetabolites as biomarkers of synthetic opioid use.J Anal Toxicol. 2010; 34: 444-449
- Sustained-release buprenorphine (RBP-6000) blocks the effects of opioid challenge with hydromorphone in subjects with opioid use disorder.J Clin Psychopharmacol. 2016; 36: 18-26
- Opioid metabolism and clinical aspects.Eur J Pharmacol. 2015; 769: 71-78
- Hydromorphone-3-glucuronide: a more potent neuro-excitant than its structural analogue, morphine-3-glucuronide.Life Sci. 2001; 69: 409-420
- Influence of renal failure on the disposition of morphine, morphine-3-glucuronide and morphine-6-glucuronide in sheep during intravenous infusion with morphine.J Pharmacol Exp Ther. 1997; 282: 779-786
- Bedside perspectives on the use of opioids: transferring results of clinical research into practice.Clin Exp Pharmacol Physiol. 2000; 27: 529-532
- Variability in UDP-glucuronosyltransferase genes and morphine metabolism: observations from a cross-sectional multicenter study in advanced cancer patients with pain.Pharmacogenet Genomics. 2013; 23: 117-126
- Drug testing: a white paper of the American society of addiction medicine.ASAM, Chevy Chase (MD)2013: 108
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- CDC guideline for prescribing opioids for chronic pain - United States, 2016.MMWR Recomm Rep. 2016; 65: 1-49
- Molecular basis of ethnic differences in drug disposition and response.Annu Rev Pharmacol Toxicol. 2001; 41: 815-850
- CYP2D6 allele frequency in european caucasians, asians, africans and their descendants.Pharmacogenomics. 2002; 3: 229-243
- PM frequencies of major CYPs in asians and caucasians.Drug Metab Rev. 2003; 35: 99-106
- Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population.Pharmacogenomics. 2004; 5: 895-931
- CYP3A5 genetic polymorphisms in different ethnic populations.Drug Metab Dispos. 2005; 33: 884-887
- Pharmacogenomics in admixed populations.Trends Pharmacol Sci. 2005; 26: 196-201
- CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure.Pharmacogenet Genomics. 2007; 17: 93-101