Review Article| Volume 35, ISSUE 3, P617-627, September 2015

Hematological Assessment in Pet Rabbits

Blood Sample Collection and Blood Cell Identification


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      1. American Veterinary Medical Association. U.S. pet ownership & demographic sourcebook. Schaumberg (IL): AVMA; 2012.

        • Carpenter J.W.
        • Mashima T.Y.
        • Gentz E.J.
        • et al.
        Caring for rabbits: an overview and formulary.
        Vet Med. 1995; 90: 340-364
        • Hawk C.T.
        • Leary S.
        Formulary for laboratory animals.
        3rd edition. Wiley-Blackwell, Ames (IA)2005
        • Dyer S.M.
        • Cervasio E.L.
        An overview of restraint and blood collection techniques in exotic pet practice.
        Vet Clin North Am Exot Anim Pract. 2008; 11: 423-443
        • Murray M.J.
        Rabbit and ferret sampling and artifact considerations.
        in: Fudge A.M. Laboratory medicine avian and exotic pets. Saunders, Philadelphia2000: 265-268
        • Mitruka B.J.
        • Rawnsley H.M.
        Clinical biochemical and hematological reference values in normal experimental animals.
        Masson Publishing, New York1977
        • Ameri M.
        • Schnaars H.A.
        • Sibley J.R.
        • et al.
        Stability of hematologic analytes in monkey, rabbit, rat, and mouse blood stored at 4°C in EDTA using the ADVIA 120 hematology analyzer.
        Vet Clin Pathol. 2011; 40: 188-194
        • Jain N.C.
        Normal values in blood of laboratory, furbearing and miscellaneous zoo, domestic and wild animals.
        in: Jain N.C. Schalm’s veterinary hematology. Lea & Febiger, Philadelphia1986: 274-343
        • Hawkey C.M.
        • Dennett T.B.
        Color atlas of comparative veterinary hematology.
        Iowa State University Press, Ames (IA)1989
        • Schermer S.
        The blood morphology of laboratory animals.
        Davis Company, Philadelphia1967
        • Zimmerman K.L.
        • Moore D.M.
        • Smith S.T.
        Hematology of laboratory rabbits.
        in: Weiss D.J. Wardrop K.J. Schalm’s, Veterinary Hematology. Lippincott Williams and Wilkins, Philadelphia2010: 862
        • Balin A.
        • Koren G.
        • Hasu M.
        • et al.
        Evaluation of a new method for the prevention of neonatal anemia.
        Pediatr Res. 1989; 25: 274
        • Bartolotti A.
        • Castelli D.
        • Bonati M.
        Hematology and serum chemistry of adult, pregnant, and newborn New Zealand rabbits (Oryctolagus cuniculus).
        Lab Anim Sci. 1989; 39: 437
        • Kozma C.
        • Macklin L.M.
        • Cummins R.
        • et al.
        Anatomy, physiology, and biochemistry of the rabbit.
        in: Weisbroth S.H. Flatt R.E. Kraus A.L. The biology of the laboratory rabbit. Academic Press, Orlando (FL)1974: 64
        • McLaughlin R.M.
        • Fish R.E.
        Clinical biochemistry and hematology.
        in: Manning P.J. Ringler D.H. Newcomer C.E. The biology of the laboratory rabbit. 2nd edition. Academic Press, San Diego (CA)1994: 119-124
        • Washington I.M.
        • Van Hoosier G.M.
        Clinical biochemistry and hematology.
        in: Suckow M.A. Stevens K.A. Wilson R.P. The laboratory rabbit, guinea pig, hamster, and other rodents. Academic Press, 2012: 97-100
        • Benson K.G.
        • Paul-Murphy J.
        Clinical pathology of the domestic rabbit.
        Vet Clin North Am Exot Anim Pract. 1999; 2 (542)
        • Reagan W.J.
        • Irizarry Rovira A.R.
        • DeNicola D.B.
        • et al.
        Normal white cell morphology.
        in: Reagan W.J. Rovira A.R.I. DeNicola D.B. Veterinary hematology: atlas of common domestic and non-domestic species. Blackwell, Ames (IA)2008: 29-35
        • Etim N.N.
        • Williams M.E.
        • Akpabio U.
        • et al.
        Haematological parameters and factors affecting their values.
        Agricultural Science. 2014; 2: 40
        • Marshall K.L.
        Rabbit hematology.
        Vet Clin North Am Exot Anim Pract. 2008; 11: 551-567
        • Nakyinsige K.
        • Sazili A.Q.
        • Aghwan Z.A.
        • et al.
        Changes in blood constituents of rabbits subjected to transportation under hot, humid tropical conditions.
        Asian-Australas J Anim Sci. 2013; 26: 874-878
        • Costa-Freitas F.L.
        • Yamamoto B.L.
        • Freitas W.L.
        • et al.
        Systemic inflammatory response indicators in rabbits experimentally infected with sporulate oocysts of Eimeria stiedai.
        Rev Bras Parasitol Vet. 2011; 20: 121-126
        • Jacobson H.A.
        • Kirkpatrick R.L.
        • Burkhart H.E.
        • et al.
        Hematologic comparisons of shot and live trapped cottontail rabbits.
        J Wildl Dis. 1978; 14: 82-88
        • Kramp W.J.
        Herpesvirus sylvilagus infects both B and T lymphocytes in vivo.
        J Virol. 1985; 56: 60-65
        • Lepitzki D.A.
        • Woolf A.
        Hematology and serum chemistry of cottontail rabbits of southern Illinois.
        J Wildl Dis. 1978; 27: 82-88