Advertisement
Review Article| Volume 35, ISSUE 3, P555-566, September 2015

Using Cardiac Biomarkers in Veterinary Practice

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.

      Subscribe:

      Subscribe to Clinics in Laboratory Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Ljungvall I.
        • Hoglund K.
        • Tidholm A.
        • et al.
        Cardiac troponin I is associated with severity of myxomatous mitral valve disease, age, and C-reactive protein in dogs.
        J Vet Intern Med. 2010; 24: 153-159
        • Hezzell M.J.
        • Boswood A.
        • Chang Y.M.
        • et al.
        The combined prognostic potential of serum high-sensitivity cardiac troponin I and N-terminal pro-B-type natriuretic peptide concentrations in dogs with degenerative mitral valve disease.
        J Vet Intern Med. 2012; 26: 302-311
        • Nagarajan V.
        • Hernandez A.V.
        • Tang W.H.
        Prognostic value of cardiac troponin in chronic stable heart failure: a systematic review.
        Heart. 2012; 98: 1778-1786
        • Sharkey L.C.
        • Berzina I.
        • Ferasin L.
        • et al.
        Evaluation of serum cardiac troponin I concentration in dogs with renal failure.
        J Am Vet Med Assoc. 2009; 234: 767-770
        • Oyama M.A.
        • Sisson D.D.
        Cardiac troponin-I concentration in dogs with cardiac disease.
        J Vet Intern Med. 2004; 18: 831-839
        • DeFrancesco T.C.
        • Rush J.E.
        • Rozanski E.A.
        • et al.
        Prospective clinical evaluation of an ELISA B-type natriuretic peptide assay in the diagnosis of congestive heart failure in dogs presenting with cough or dyspnea.
        J Vet Intern Med. 2007; 21: 243-250
        • Oyama M.A.
        • Fox P.R.
        • Rush J.E.
        • et al.
        Clinical utility of serum N-terminal pro-B-type natriuretic peptide concentration for identifying cardiac disease in dogs and assessing disease severity.
        J Am Vet Med Assoc. 2008; 232: 1496-1503
        • Connolly D.J.
        • Magalhaes R.J.
        • Syme H.M.
        • et al.
        Circulating natriuretic peptides in cats with heart disease.
        J Vet Intern Med. 2008; 22: 96-105
        • Menaut P.
        • Connolly D.J.
        • Volk A.
        • et al.
        Circulating natriuretic peptide concentrations in hyperthyroid cats.
        J Small Anim Pract. 2012; 53: 673-678
        • Kellihan H.B.
        • Mackie B.A.
        • Stepien R.L.
        NT-proBNP, NT-proANP and cTnI concentrations in dogs with pre-capillary pulmonary hypertension.
        J Vet Cardiol. 2011; 13: 171-182
        • Prosek R.
        • Sisson D.D.
        • Oyama M.A.
        • et al.
        Distinguishing cardiac and noncardiac dyspnea in 48 dogs using plasma atrial natriuretic factor, B-type natriuretic factor, endothelin, and cardiac troponin-I.
        J Vet Intern Med. 2007; 21: 238-242
        • Oyama M.A.
        • Rush J.E.
        • Rozanski E.A.
        • et al.
        Assessment of serum N-terminal pro-B-type natriuretic peptide concentration for differentiation of congestive heart failure from primary respiratory tract disease as the cause of respiratory signs in dogs.
        J Am Vet Med Assoc. 2009; 235: 1319-1325
        • Connolly D.J.
        • Soares Magalhaes R.J.
        • Fuentes V.L.
        • et al.
        Assessment of the diagnostic accuracy of circulating natriuretic peptide concentrations to distinguish between cats with cardiac and non-cardiac causes of respiratory distress.
        J Vet Cardiol. 2009; 11: S41-S50
        • Fox P.R.
        • Oyama M.A.
        • Reynolds C.
        • et al.
        Utility of plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) to distinguish between congestive heart failure and non-cardiac causes of acute dyspnea in cats.
        J Vet Cardiol. 2009; 11: S51-S61
        • Singletary G.E.
        • Rush J.E.
        • Fox P.R.
        • et al.
        Effect of NT-pro-BNP assay on accuracy and confidence of general practitioners in diagnosing heart failure or respiratory disease in cats with respiratory signs.
        J Vet Intern Med. 2012; 26: 542-546
        • O'Grady M.R.
        • O'Sullivan M.L.
        Dilated cardiomyopathy: an update.
        Vet Clin North Am Small Anim Pract. 2004; 34: 1187-1207
        • Trehiou-Sechi E.
        • Tissier R.
        • Gouni V.
        • et al.
        Comparative echocardiographic and clinical features of hypertrophic cardiomyopathy in 5 breeds of cats: a retrospective analysis of 344 cases (2001-2011).
        J Vet Intern Med. 2012; 26: 532-541
        • Wess G.
        • Butz V.
        • Mahling M.
        • et al.
        Evaluation of N-terminal pro-B-type natriuretic peptide as a diagnostic marker of various stages of cardiomyopathy in Doberman pinschers.
        Am J Vet Res. 2011; 72: 642-649
        • Singletary G.E.
        • Morris N.A.
        • O'Sullivan M.L.
        • et al.
        Prospective evaluation of NT-proBNP assay to detect occult dilated cardiomyopathy and predict survival in Doberman pinschers.
        J Vet Intern Med. 2012; 26: 1330-1336
        • Oyama M.A.
        • Sisson D.D.
        • Solter P.F.
        Prospective screening for occult cardiomyopathy in dogs by measurement of plasma atrial natriuretic peptide, B-type natriuretic peptide, and cardiac troponin-I concentrations.
        Am J Vet Res. 2007; 68: 42-47
        • Fox P.R.
        • Rush J.E.
        • Reynolds C.A.
        • et al.
        Multicenter evaluation of plasma N-terminal probrain natriuretic peptide (NT-pro BNP) as a biochemical screening test for asymptomatic (occult) cardiomyopathy in cats.
        J Vet Intern Med. 2011; 25: 1010-1016
        • Wess G.
        • Daisenberger P.
        • Mahling M.
        • et al.
        Utility of measuring plasma N-terminal pro-brain natriuretic peptide in detecting hypertrophic cardiomyopathy and differentiating grades of severity in cats.
        Vet Clin Pathol. 2011; 40: 237-244
        • Tominaga Y.
        • Miyagawa Y.
        • Toda N.
        • et al.
        The diagnostic significance of the plasma N-terminal pro-B-type natriuretic peptide concentration in asymptomatic cats with cardiac enlargement.
        J Vet Med Sci. 2011; 73: 971-975
        • Chetboul V.
        • Serres F.
        • Tissier R.
        • et al.
        Association of plasma N-terminal pro-B-type natriuretic peptide concentration with mitral regurgitation severity and outcome in dogs with asymptomatic degenerative mitral valve disease.
        J Vet Intern Med. 2009; 23: 984-994
        • Reynolds C.A.
        • Brown D.C.
        • Rush J.E.
        • et al.
        Prediction of first onset of congestive heart failure in dogs with degenerative mitral valve disease: the PREDICT cohort study.
        J Vet Cardiol. 2012; 14: 193-202
        • Moonarmart W.
        • Boswood A.
        • Luis F.
        • et al.
        N-terminal pro B-type natriuretic peptide and left ventricular diameter independently predict mortality in dogs with mitral valve disease.
        J Small Anim Pract. 2010; 51: 84-96
        • Noszczyk-Nowak A.
        NT-pro-BNP and troponin I as predictors of mortality in dogs with heart failure.
        Pol J Vet Sci. 2011; 14: 551-556
        • Rishniw M.
        • Ljungvall I.
        • Porciello F.
        • et al.
        Sleeping respiratory rates in apparently healthy adult dogs.
        Res Vet Sci. 2012; 93: 965-969
        • Schober K.E.
        • Hart T.M.
        • Stern J.A.
        • et al.
        Detection of congestive heart failure in dogs by Doppler echocardiography.
        J Vet Intern Med. 2010; 24: 1358-1368
        • Porapakkham P.
        • Porapakkham P.
        • Zimmet H.
        • et al.
        B-type natriuretic peptide-guided heart failure therapy: a meta-analysis.
        Arch Intern Med. 2010; 170: 507-514
        • Felker G.M.
        • Hasselblad V.
        • Hernandez A.F.
        • et al.
        Biomarker-guided therapy in chronic heart failure: a meta-analysis of randomized controlled trials.
        Am Heart J. 2009; 158: 422-430
        • Wolf J.
        • Gerlach N.
        • Weber K.
        • et al.
        Lowered N-terminal pro-B-type natriuretic peptide levels in response to treatment predict survival in dogs with symptomatic mitral valve disease.
        J Vet Cardiol. 2012; 14: 399-408
        • Herndon W.E.
        • Kittleson M.D.
        • Sanderson K.
        • et al.
        Cardiac troponin I in feline hypertrophic cardiomyopathy.
        J Vet Intern Med. 2002; 16: 558-564
        • Connolly D.J.
        • Cannata J.
        • Boswood A.
        • et al.
        Cardiac troponin I in cats with hypertrophic cardiomyopathy.
        J Feline Med Surg. 2003; 5: 209-216
        • Herndon W.E.
        • Rishniw M.
        • Schrope D.
        • et al.
        Assessment of plasma cardiac troponin I concentration as a means to differentiate cardiac and noncardiac causes of dyspnea in cats.
        J Am Vet Med Assoc. 2008; 233: 1261-1264
        • Miyagawa Y.
        • Tominaga Y.
        • Toda N.
        • et al.
        Relationship between glomerular filtration rate and plasma N-terminal pro B-type natriuretic peptide concentrations in dogs with chronic kidney disease.
        Vet J. 2013; (in press)
        • Lalor S.M.
        • Connolly D.J.
        • Elliott J.
        • et al.
        Plasma concentrations of natriuretic peptides in normal cats and normotensive and hypertensive cats with chronic kidney disease.
        J Vet Cardiol. 2009; 11: S71-S79
        • Fine D.M.
        • Declue A.E.
        • Reinero C.R.
        Evaluation of circulating amino-terminal-pro-B-type natriuretic peptide concentration in dogs with respiratory distress attributable to congestive heart failure or primary pulmonary disease.
        J Am Vet Med Assoc. 2008; 232: 1674-1679