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Review Article| Volume 31, ISSUE 2, P255-265, June 2011

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Dysplastic Nevi

  • Loren E. Clarke
    Correspondence
    Department of Pathology, H179, The Penn State Hershey Medical Center, Hershey, PA 17033, USA.
    Affiliations
    Departments of Pathology, H179, The Penn State Hershey Medical Center, Hershey, PA 17033, USA

    Department of Dermatology, The Penn State Hershey Medical Center, Hershey, PA 17033, USA
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      References

        • Clark Jr., W.H.
        • Reimer R.R.
        • Greene M.
        • et al.
        Origin of familial malignant melanomas from heritable melanocytic lesions. ‘The B-K mole syndrome’.
        Arch Dermatol. 1978; 114: 732-738
        • Ackerman A.B.
        What naevus is dysplastic, a syndrome and the commonest precursor of malignant melanoma? A riddle and an answer.
        Histopathology. 1988; 13: 241-256
        • Glusac E.J.
        What to call the LEJC-BFV nevus?.
        J Cutan Pathol. 2004; 31: 521-522
        • Ackerman A.B.
        • Magana-Garcia M.
        Naming acquired melanocytic nevi. Unna's, Miescher's, Spitz's Clark's.
        Am J Dermatopathol. 1990; 12: 193-209
        • NIH Consensus Conference
        Diagnosis and treatment of early melanoma.
        JAMA. 1992; 268: 1314-1319
        • Shapiro M.
        • Chren M.M.
        • Levy R.M.
        • et al.
        Variability in nomenclature used for nevi with architectural disorder and cytologic atypia (microscopically dysplastic nevi) by dermatologists and dermatopathologists.
        J Cutan Pathol. 2004; 31: 523-530
        • Tripp J.M.
        • Kopf A.W.
        • Marghoob A.A.
        • et al.
        Management of dysplastic nevi: a survey of fellows of the American Academy of Dermatology.
        J Am Acad Dermatol. 2002; 46: 674-682
        • Gandini S.
        • Sera F.
        • Cattaruzza M.S.
        • et al.
        Meta-analysis of risk factors for cutaneous melanoma: I. Common and atypical naevi.
        Eur J Cancer. 2005; 41: 28-44
        • Carey Jr., W.P.
        • Thompson C.J.
        • Synnestvedt M.
        • et al.
        Dysplastic nevi as a melanoma risk factor in patients with familial melanoma.
        Cancer. 1994; 74: 3118-3125
        • Halpern A.C.
        • Guerry D.T.
        • Elder D.E.
        • et al.
        Dysplastic nevi as risk markers of sporadic (nonfamilial) melanoma. A case-control study.
        Arch Dermatol. 1991; 127: 995-999
        • Lynch H.T.
        • Frichot 3rd, B.C.
        • Lynch J.F.
        Familial atypical multiple mole-melanoma syndrome.
        J Med Genet. 1978; 15: 352-356
        • Lynch H.T.
        • Fusaro R.M.
        • Lynch J.F.
        A medical and genetic critique of the familial atypical multiple mole melanoma syndrome and the dysplastic nevus syndrome.
        Am J Dermatopathol. 1985; 7: S107-S116
        • Lynch H.T.
        • Fusaro R.M.
        • Pester J.
        • et al.
        Familial atypical multiple mole melanoma (FAMMM) syndrome: genetic heterogeneity and malignant melanoma.
        Br J Cancer. 1980; 42: 58-70
        • Lynch H.T.
        • Fusaro R.M.
        • Treger C.L.
        • et al.
        The cutaneous evolution of nevi in a patient with familial, atypical, multiple-mole melanoma syndrome.
        Pediatr Dermatol. 1985; 2: 289-293
        • Kraemer K.H.
        • Greene M.H.
        • Tarone R.
        • et al.
        Dysplastic naevi and cutaneous melanoma risk.
        Lancet. 1983; 2: 1076-1077
        • Roth M.E.
        • Grant-Kels J.M.
        • Ackerman A.B.
        • et al.
        The histopathology of dysplastic nevi. Continued controversy.
        Am J Dermatopathol. 1991; 13: 38-51
        • Kelly J.W.
        • Crutcher W.A.
        • Sagebiel R.W.
        Clinical diagnosis of dysplastic melanocytic nevi. A clinicopathologic correlation.
        J Am Acad Dermatol. 1986; 14: 1044-1052
        • Rhodes A.R.
        • Mihm Jr., M.C.
        • Weinstock M.A.
        Dysplastic melanocytic nevi: a reproducible histologic definition emphasizing cellular morphology.
        Mod Pathol. 1989; 2: 306-319
        • Toussaint S.
        • Kamino H.
        Dysplastic changes in different types of melanocytic nevi. A unifying concept.
        J Cutan Pathol. 1999; 26: 84-90
        • Shors A.R.
        • Kim S.
        • White E.
        • et al.
        Dysplastic naevi with moderate to severe histological dysplasia: a risk factor for melanoma.
        Br J Dermatol. 2006; 155: 988-993
        • Weinstock M.A.
        • Barnhill R.L.
        • Rhodes A.R.
        • et al.
        Reliability of the histopathologic diagnosis of melanocytic dysplasia. The Dysplastic Nevus Panel.
        Arch Dermatol. 1997; 133: 953-958
        • Piepkorn M.W.
        • Barnhill R.L.
        • Cannon-Albright L.A.
        • et al.
        A multiobserver, population-based analysis of histologic dysplasia in melanocytic nevi.
        J Am Acad Dermatol. 1994; 30: 707-714
        • Duncan L.M.
        • Berwick M.
        • Bruijn J.A.
        • et al.
        Histopathologic recognition and grading of dysplastic melanocytic nevi: an interobserver agreement study.
        J Invest Dermatol. 1993; 100: 318S-321S
        • Lodha S.
        • Saggar S.
        • Celebi J.T.
        • et al.
        Discordance in the histopathologic diagnosis of difficult melanocytic neoplasms in the clinical setting.
        J Cutan Pathol. 2008; 35: 349-352
        • Farmer E.R.
        • Gonin R.
        • Hanna M.P.
        Discordance in the histopathologic diagnosis of melanoma and melanocytic nevi between expert pathologists.
        Hum Pathol. 1996; 27: 528-531
        • Arumi-Uria M.
        • McNutt N.S.
        • Finnerty B.
        Grading of atypia in nevi: correlation with melanoma risk.
        Mod Pathol. 2003; 16: 764-771
        • Maize Jr., J.C.
        • Resneck Jr., J.S.
        • Shapiro P.E.
        • et al.
        Ducking stray “magic bullets”: a Melan-A alert.
        Am J Dermatopathol. 2003; 25: 162-165
        • Tucker M.A.
        • Fraser M.C.
        • Goldstein A.M.
        • et al.
        A natural history of melanomas and dysplastic nevi: an atlas of lesions in melanoma-prone families.
        Cancer. 2002; 94: 3192-3209
        • Sellheyer K.
        • Bergfeld W.F.
        • Stewart E.
        • et al.
        Evaluation of surgical margins in melanocytic lesions: a survey among 152 dermatopathologists.
        J Cutan Pathol. 2005; 32: 293-299
        • Cockerell C.J.G.-K.J.
        • Canther J.C.
        • LeBoit P.
        Pathology and genetics of skin tumours.
        IARC Press, Lyon2006
        • Holly E.A.
        • Kelly J.W.
        • Shpall S.N.
        • et al.
        Number of melanocytic nevi as a major risk factor for malignant melanoma.
        J Am Acad Dermatol. 1987; 17: 459-468
        • Tucker M.A.
        • Halpern A.
        • Holly E.A.
        • et al.
        Clinically recognized dysplastic nevi. A central risk factor for cutaneous melanoma.
        JAMA. 1997; 277: 1439-1444