Cancer is the third leading cause of death in the United States and ranks among the
top five causes of death worldwide. Scientists have searched for an infectious etiology
of malignancies with little success. Although epidemiologic studies have suggested
links between various biologic agents and certain malignancies, it has been the recent
advances in molecular biology techniques that have led to the discovery of several
examples of viral, bacterial, and even parasitic organisms as carcinogenic agents.
The etiology of neoplastic diseases such as adult T-cell leukemia, hepatocellular
carcinoma, and mucosa-associated lymphoid tissue (MALT) lymphoma has been attributed
directly to human T-cell leukemia virus, hepatitis B and C, and Helicobacter pylori respectively.
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© 2003 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
