Advertisement
Review Article| Volume 22, ISSUE 1, P137-151, March 2002

Peripheral blood findings in chronic myeloproliferative disorders

  • Michele Imbert
    Correspondence
    Address reprint requests to: Michele Imbert, MD Laboratory of Hematology Paris XII University and Henri Mondor Hospital 51, avenue du Mal de Lattre-de-Tassigny 94010-CréteilFrance
    Affiliations
    Laboratory of Hematology, Paris XII University and Henri Mondor Hospital, Créteil, France
    Search for articles by this author
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.

      Subscribe:

      Subscribe to Clinics in Laboratory Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Adamson JW
        • Fialkow PJ
        • Murphy S
        • et al.
        Polycythemia vera: Stem-cell and probable clonal origin of the disease.
        N Engl J Med. 1976; 295: 913-916
        • Anger B
        • Janssen JWG
        • Schrezenmeier H
        • et al.
        Clonal analysis of chronic myeloproliferative disorders using X-linked DNA polymorphisms.
        Leukemia. 1990; 4: 258-261
        • Ania BJ
        • Suman VJ
        • Sobell JL
        • et al.
        Trends in the incidence of polycythemia vera among Omsted County, Minnesota residents, 1935–1989.
        Am J Hematol. 1994; 47: 89-93
        • Bain BJ
        Eosinophilic leukemias and the hypereosinophilic syndrome.
        Br J Haematol. 1996; 95: 2-9
        • Bain B
        • Pierre R
        • Imbert M
        • et al.
        Chronic eosinophilic leukemia and the hypereosinophilic syndrome.
        in: Jaffe ES Harris NL Stein H The World Health Organization of Classification of Tumors: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press, Lyon2001: 29-31
        • Bartram CR
        • de Klein A
        • Hagemeijer A
        • et al.
        Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia.
        Nature. 1983; 306: 277-280
        • Bellucci S
        • Janvier M
        • Tobelem G
        • et al.
        Essential thrombocythemias: Clinical evolutionary and biological data.
        Cancer. 1986; 58: 2440-2447
        • Bennett J
        • Catovski D
        • Daniel MT
        • et al.
        The chronic myeloid leukemias: Guidelines for distinguishing chronic granulocytic, atypical chronic myeloid, and chronic myelo monocytic leukaemia: Proposals by the French-American-British cooperative leukaemia group.
        Br J Haematol. 1994; 87: 746-754
        • Berk PD
        • Goldberg JD
        • Donovan PB
        • et al.
        Therapeutic recommendations in polycythemia vera based on Polycythemia Vera Study Group protocols.
        Semin Hematol. 1986; 23: 132-143
        • Berlin NI
        Diagnosis and classification of the polycythemias.
        Semin Hematol. 1975; 12: 339-351
        • Bettelheim P
        • Lutz D
        • Majdic O
        • et al.
        Cell lineage heterogeneity in blast crisis of chronic myeloid leukaemia.
        Br J Haematol. 1985; 59: 395-409
        • Bilgrami S
        • Greenberg BR
        Polycythemia rubra vera.
        Semin Oncol. 1995; 22: 307-326
        • Cervantes C
        • Barosi G
        • Demory JL
        • et al.
        Myelofibrosis with myeloid metaplasia in young individuals: Disease characteristics, prognostic factors and identification of risk groups.
        Br J Haematol. 1998; 102: 684-690
        • Di Donato C
        • Croci G
        • Lazzari S
        • et al.
        Chronic neutrophilic leukemia: Description of a new case with karyotypic abnormalities.
        Am J Clin Pathol. 1986; 85: 369-371
        • Dupriez B
        • Morel P
        • Demory JL
        • et al.
        Prognostic factors in agnogenic myeloid metaplasia: A report on 195 cases with a new scoring system.
        Blood. 1996; 88: 1013-1018
        • Ellis JT
        • Peterson P
        Myelofibrosis in the myeloproliferative disorders.
        in: Berk PD Castro-Malaspina H Wasserman LR Myelofibrosis and the Biology of Connective Tissue. AR Liss, New York1984: 19-42
        • Faderl S
        • Talpaz M
        • Estrov Z
        • et al.
        Chronic myelogenous leukemia: Biology and therapy.
        Ann Intern Med. 1999; 131: 207-219
        • Fenaux P
        • Simon M
        • Caulier MT
        • et al.
        Clinical course of essential thrombocythemia in 147 cases.
        Cancer. 1990; 66: 549-556
        • Fialkow PJ
        • Faguet GB
        • Jacobson RJ
        • et al.
        Evidence that essential thrombocythemia is a clonal disorder with origin in a multipotent stem cell.
        Blood. 1981; 58: 916-918
        • Fialkow PJ
        • Jacobson RJ
        • Papayannopoulou T
        Chronic myelocytic leukemia: Clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/ macrophage.
        Am J Med. 1977; 63: 125-130
        • Greenberg BR
        • Woo L
        • Veomett IC
        • et al.
        Cytogenetics of bone marrow fibroblastic cells in idiopathic chronic myelofibrosis.
        Br J Haematol. 1987; 66: 487-490
        • Groffen J
        • Stephenson JR
        • Heisterkamp N
        • et al.
        Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22.
        Cell. 1984; 36: 93-99
        • Gruppo Italiano Studio Policitemia
        Polycythemia vera: The natural history of 1213 patients followed for 20 years.
        Ann Intern Med. 1995; 125: 656-664
        • Hasle H
        • Olesen G
        • Kerndrup G
        • et al.
        Chronic neutrophil leukaemia in adolescence and young adulthood.
        Br J Haematol. 1996; 94: 628-630
        • Hernandez JM
        • Del Canizo MC
        • Cuneo A
        • et al.
        Clinical, hematological and cytogenetic characteristics of atypical chronic myeloid leukemia.
        Ann Oncol. 2000; 11: 441-444
        • Imbert M
        • Bain B
        • Pierre R
        • et al.
        Chronic neutrophilic leukaemia.
        in: Jaffe ES Harris NL Stein H The World Health Organization of Classification of Tumors: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press, Lyon2001: 27-28
        • Imbert M
        • Pierre R
        • Thiele J
        • et al.
        Essential thrombocythaemia.
        in: Jaffe ES Harris NL Stein H The World Health Organization of Classification of Tumors: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press, Lyon2001: 39-41
        • Jacobson RJ
        • Salo A
        • Fialkow PJ
        Agnogenic myeloid metaplasia: A clonal proliferation of hematopoietic stem cells with secondary myelofibrosis.
        Blood. 1978; 51: 189-194
        • Kantarjian HM
        • Keating MJ
        • Talpaz M
        • et al.
        Chronic myelogenous leukemia in blast crisis: Analysis of 242 patients.
        Am J Med. 1987; 83: 445-454
        • Khalidi HS
        • Brynes RK
        • Medeiros LJ
        • et al.
        The immunophenotype of blast transformation of chronic myelogenous leukemia: A high frequency of mixed lineage phenotype in “lymphoid” blasts and a comparison of morphologic, immunophenotypic, and molecular findings.
        Mod Pathol. 1998; 11: 1211-1221
        • Lewis SM
        • Szur L
        Malignant myelosclerosis.
        BMJ. 1963; 2: 472-477
        • Maldonado JE
        • Pintado T
        • Pierre RV
        Dysplastic platelets and circulating megakaryocytes in chronic myeloproliferative disease. I. The platelets: Ultrastructural and peroxidase reaction.
        Blood. 1974; 43: 797-803
        • Martin PJ
        • Najfeld V
        • Hansen JA
        • et al.
        Involvement of the B-lymphoid system in chronic myelogenous leukemia.
        Nature. 1980; 287: 49-50
        • McIntyre KJ
        • Hoagland HC
        • Silverstein MN
        • et al.
        Essential thrombocythemia in young adults.
        Mayo Clin Proc. 1991; 66: 149-154
        • Melo JV
        The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype.
        Blood. 1996; 88: 2375-2384
        • Melo J
        • Myint H
        • Galton D
        • et al.
        P190BCR-ABL chronic myeloid leukemia: The missing link with chronic myelomonocytic leukemia?.
        Leukemia. 1994; 8: 208-224
        • Mesa RA
        • Silverstein MN
        • Jacobsen SJ
        • et al.
        Population-based incidence and survival figures in essential thrombocythemia and agnogenic myeloid metaplasia: An On Olmsted County Study, 1976–1995.
        Am J Hematol. 1999; 61: 10-15
        • Muehleck SD
        • McKenna RW
        • Arthur DC
        • et al.
        Transformation of chronic myelogenous leukemia: Clinical, morphologic and cytogenetic features.
        Am J Clin Pathol. 1984; 82: 1-14
        • Murphy S
        Diagnostic criteria and prognosis in polycythemia vera and essential thrombocythemia.
        Semin Hematol. 1999; 36: 9-13
        • Murphy S
        • Peterson P
        • Iland H
        • et al.
        Experience of the polycythemia vera study group with essential thrombocythemia: A final report on diagnostic criteria, survival, and leukemic transition by treatment.
        Semin Hematol. 1997; 34: 29-39
        • Nair C
        • Chopra H
        • Shinde S
        • et al.
        Immunophenotype and ultrastructural studies in blast crisis of chronic myeloid leukemia.
        Leuk Lymphoma. 1995; 19: 309-313
        • Najean Y
        • Rain JD
        The very long term evolution of polycythemia vera: An analysis of 318 patients initially treated by phlebotomy or 32P between 1969 and 1981.
        Semin Hematol. 1997; 34: 6-16
        • Nowel PC
        • Hungerford DA
        A minute chromosome in human chronic granulocytic leukemia.
        Science. 1960; 132: 1497-1498
        • Okun DB
        • Tanaka KR
        Leukocyte alkaline phosphatase.
        Am J Hematol. 1978; 4: 293-299
        • Pane F
        • Frigeri F
        • Sindona M
        • et al.
        Neutrophilic-chronic myeloid leukemia: A distinct disease with a specific molecular marker (BCR/ABL with C3/A2 junction).
        Blood. 1996; 88: 2410-2414
        • Pierre R
        • Imbert M
        • Thiele J
        • et al.
        Polycythemia vera.
        in: Jaffe ES Harris NL Stein H The World Health Organization of Classification of Tumors: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press, Lyon2001: 32-34
        • Randi ML
        • Putti MC
        • Fabris F
        • et al.
        Features of essential thrombocythaemia in childhood: A study of five children.
        Br J Haematol. 2000; 108: 86-89
        • Rosenthal S
        • Canellos GP
        • de Vita VT
        • et al.
        Characteristics of blast crisis in chronic granulocytic leukemia.
        Blood. 1977; 49: 705-714
        • Rowley JD
        A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining.
        Nature. 1973; 243: 290-293
        • Saikia T
        • Advani S
        • Dasgupta A
        • et al.
        Characterization of blast cells during blastic phase of chronic myeloid leukaemia by immunophenotyping—experience in 60 patients.
        Leuk Res. 1988; 12: 499-506
        • Savage DG
        • Szydlo RH
        • Goldman JM
        Clinical features at diagnosis in 430 patients with chronic myeloid leukemia seen at a referral center over a 16-year period.
        Br J Haematol. 1997; 96: 111-116
        • Spiers AS
        • Bain BJ
        • Turner JE
        The peripheral blood in chronic granulocytic leukemia: Study of 50 untreated Philadelphia-positive cases.
        Scand J Haematol. 1977; 18: 25-38
        • Sultan C
        • Sigaux F
        • Imbert M
        • et al.
        Acute myelodysplasia with myelofibrosis: A report of eight cases.
        Br J Haematol. 1981; 49: 11-16
        • Tefferi Y
        Myelofibrosis with myeloid metaplasia.
        N Engl J Med. 2000; 342: 1255-1265
        • Thiele J
        • Imbert M
        • Pierre R
        • et al.
        Chronic myeloproliferative disease, unclassifiable.
        in: Jaffe ES Harris NL Stein H The World Health Organization of Classification of Tumors: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press, Lyon2001: 42-44
        • Thiele J
        • Pierre R
        • Imbert M
        • et al.
        Chronic idiopathic myelofibrosis.
        in: Jaffe ES Harris NL Stein H The World Health Organization of Classification of Tumors: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press, Lyon2001: 35-38
        • Vardiman JW
        • Imbert M
        • Pierre R
        • et al.
        Atypical chronic myeloid leukemia.
        in: Jaffe ES Harris NL Stein H The World Health Organization of Classification of Tumors: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press, Lyon2001: 53-54
        • Vardiman JW
        • Pierre R
        • Bain B
        • et al.
        Chronic myelomonocytic leukemia.
        in: Jaffe ES Harris NL Stein H The World Health Organization of Classification of Tumors: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press, Lyon2001: 49-52
        • Vardiman JW
        • Pierre R
        • Thiele J
        • et al.
        Chronic myelogenous leukaemia.
        in: Jaffe ES Harris NL Stein H The World Health Organization of Classification of Tumors: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press, Lyon2001: 20-26
        • Visani G
        • Finelli C
        • Castelli U
        • et al.
        Myelofibrosis with myeloid metaplasia: Clinical and haematological parameters predicting survival in a series of 133 patients.
        Br J Haematol. 1990; 75: 4-9
        • Weil SC
        • Hrisinko MA
        A hybrid eosinophilic-basophilic granulocyte in chronic granulocytic leukemia.
        Am J Clin Pathol. 1987; 87: 66-70
        • Weller PF
        • Bubley GJ
        The hypereosinophilic syndrome.
        Blood. 1994; 83: 2759-2779
        • You W
        • Weisbrot IM
        Chronic neutrophilic leukemia: Report of two cases and review of the literature.
        Am J Clin Pathol. 1979; 72: 233-242
        • Zittoun R
        • Rea D
        • Ngoc LH
        • et al.
        Chronic neutrophilic leukemia: A study of four cases.
        Ann Hematol. 1994; 68: 55-60