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Review article| Volume 23, ISSUE 2, P317-343, June 2003

Testing for hematologic disorders and complications

      In recent years, the laboratory evaluation of fetal blood cell disorders has assumed a greater role in antenatal diagnosis and management. The introduction of percutaneous blood sampling in the 1980s [
      • Daffos F.
      • Capella-Pavlovsky M.
      • Forestier F.
      Fetal blood sampling during pregnancy with use of a needle guided by ultrasound: a study of 606 consecutive cases.
      ] allowed the description of normal and abnormal fetal hematologic values [
      • Forestier F.
      • Daffos F.
      • Galacteros F.
      • Bardakjian J.
      • Rainaut M.
      • Beuzard Y.
      Hematological values of 163 normal fetuses between 18 and 30 weeks of gestation.
      ,
      • Forestier F.
      • Daffos F.
      • Catherine N.
      • Renard M.
      • Andreux J.P.
      Developmental hematopoiesis in normal fetal blood.
      ]. In recent years, advances in clinical genetics and genomics have advanced fetal diagnosis of hemolytic and hypoplastic anemias and thrombocytopenia.
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