HIV-1 reservoirs

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• Roederer M.
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• Woods T.C.
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• Chun T.W.
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• Moriuchi H.
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Kazanjian P, Adams D, Kaul D, Armstrong W, Newman GW. HIV replication in macrophages isolated from HIV-infected patients receiving protease inhibitors [abstract 362]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

• Lambotte O.
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• deGoer M.G.
• Wallon C.
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Poles M, Elliott J, Brow S, Shi DP, Chiong S, Hege K, et al. HIV-1 is detectable in mucosal biopsies in patients with undetectable plasma viral loads [abstract 160]. Presented at the 6th Conference on Retroviruses and Opportunistic Infections. Chicago; January 30, 1999.

• Sonza S.
• Mutimer H.P.
• Oelrichs R.
• Jardine D.
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• Pomerantz R.J.

• Chun T.-W.
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• Sanchez G.
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• Fouchier R.A.M.
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Bruggeman LA, Ross MD, Tanji N, Cara A, D'Agati VD, Kikman S, et al. The kidney is a previously unrecognized reservoir for HIV-1 replication [abstract 161]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

• Huisman M.T.
• Smit J.W.
• Schinkel A.H.

• Clayette P.
• Jorajuria S.
• Dormont D.

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Gupta P, Leroux C, Patterson B, Kingsley L, Rinaldo C, Ding M, et al. HIV-1 shedding pattern in semen correlates with the compartmentalization of viral quasispecies between blood and semen [abstract 114]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

Schacker T, Pryor J, Nguyen P, Sieber C, Coombs R, Trenkner S, et al. Sites of productive infection of HIV in the male GU tract [abstract 115]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

• Zhang L.
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• Martinez M.A.
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• Furtado M.R.
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Imamichi M, Crandall K, Jiang MK, Berg S, Gaddam A, Besche A, et al. Infectious HIV-1 derived from PBMC coculture reflects a subset of transcriptionally active variants present in PBMC in patients with prolonged suppression of plasma viremia with HAART [abstract TuPeA3101]. Presented at the XIII International Conference on AIDS. Durban, South Africa, July 9–14, 2000.

Bucy RP, Kilby JM, Goepfert PA, Hockett RD, Saha BK, Saag MS. Persistent vRNA in PBMC from HIV-infected patients on potent antiretroviral therapy is associated with rare vRNA + cells [abstract 140]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

Yerly S, Perneger T-V, Vora S, Hirschel B, Perrin L. Decay rates of cellassociated HIV-1 DNA correlate with residual viral replication in patients treated during primary HIV-1 infection [abstract 210]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

• Gunthard H.F.
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Zhu T, Muthui D, Holte S, Chang Y, Nickle JD, Feng F, et al. HIV-1 latent reservoirs renewed by viral replication in activated CD4+ T lymphocytes, monocytes, and resting CD4+ T lymphocytes in patients receiving potent therapy [abstract 136]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

• Unutmaz D.
• KewalRamani V.N.
• Marmon S.
• Littman D.R.

• Zhang H.
• Zhang Y.
• Spicer T.P.
• Abbott I.Z.
• Abbott M.
• Poiesz B.J.

• Zhang H.
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• Wu Y.
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Luzuriaga K, McManus M, Catalin M, Mayack S, Sharkey M, Stevenson M, et al. Early therapy of vertical HIV-1 infection: evidence for cessation of viral replication and absence of virus-specific immunity [abstract 211]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

• Harrigan P.R.
• Whaley M.
• Montaner J.S.G.

• Montaner J.S.G.
• Harris M.
• Mo T.
• Harrigan R.P.

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Patterson BK, McCalister S, Schutz M, Siegel S, Shults K, Martin S, et al. Persistence of intracellular HIV-1 mRNA (in-cell viral load) correlates with HIV-specific immune responses in HIV-infected subjects on stable HAART therapy [abstract 784]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

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• Hockett R.D.
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• Enting R.H.
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• Portegies P.

Chun T-W, Davey R, Ostrowksi M, Engel D, Mullins J, Lane C, et al. Relationship between pre-existing latent viral reservoirs and the re-emergence of plasma viremia following discontinuation of highly active antiretroviral therapy [abstract 23]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

• Hlavacek W.S.
• Wofsy C.
• Perelson A.S.

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• Lewin S.R.
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• Goldstein H.
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Easterbrook P, Ives N, Peters B, Gazzard B. The natural history and clinical significance of intermittent virological “blips” in patients who attain an initially undetectable viral load (VL) on HAART [abstract WeOrB610]. Presented at the XIII International Conference on AIDS. Durban, South Africa, July 9–14, 2000.

Ward D, Sklar P. The significance of low-level viremia in patients with previously “undetectable” HIV-1 RNA levels [abstract MoPpB1019]. Presented at the XIII International Conference on AIDS. Durban, South Africa, July 9–14, 2000.

Blankson J, Finzi D, Pierson T, Savundayo B, Chadwick K, Margolick J, et al. Biphasic decay of latent HIV-1 in resting CD4+ T cells in acute seroconverters [abstract 137]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

Martinez-Picado J, DePasquale MP, Kartsonis NA, Hanna G, Wong J, Finzi D, et al. Selection of antiretroviral resistance in the latent reservoir of human immunodeficiency virus type 1 during successful therapy [abstract 238]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

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Altfeld M, Rosenberger ES, Eldridge RL, Poon S, Mukherjee JS, Phillips M, et al. Increase in breadth and frequency of CTL responses following structured therapy interruptions in individuals treated with HAART during acute HIV-1 infection [abstract 357]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

Altfeld M, Rosenberg ES, Mukhergee J, Eldridge RL, Poon SH, Phillips MN, et al. Enhancement of HIV-1 specific CTL responses during structured treatment interruptions (STI) following treated acute HIV-1-infection is associated with control of HIV-1 viremia [abstract ThOrB750]. Presented at the XIII International Conference on AIDS. Durban, South Africa, July 9–14, 2000.

• Berger E.A.
• Moss B.
• Pastan L.

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Brodier SJ, Berrey MM, Patterson BK, Zhu T, Diem K, Wood BL, et al. Comparison of cell-associated HIV-1 DNA and RNA in triple-drug-treated versus untreated persons with primary HIV-1: evidence for persistent viral reservoirs [abstract 561]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

• Brooks D.G.
• Kitchen S.G.
• Kitchen C.M.R.
• Scripture-Adams D.D.
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Capobianchi MR, Abbate L, Dianzani F, Turriziani O, Antonelli G, D'Offizi G, et al. Host cell-derived differentiation, activation and co-stimulatory/adhesion molecules acquired by circulating HIV-1: longitudinal analysis in patients undergoing controlled therapy interruption [abstract ThOrB749]. Presented at the XIII International Conference on AIDS. Durban, South Africa, July 9–14, 2000.

Carcelain G, Tubiana R, Mollet L, Samri A, Calvez V, Delaugerre C, et al. Intermittent interruptions of antiretroviral therapy in chronically HIV-1 infected patients do not induce immune control of HIV [abstract 356]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

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Deeks SG, Wrin T, Hoh R, Troiano J, Liegler T, Hayden M, et al. Virologic and immunologic evaluation of structured treatment interruptions (STI) in patients experiencing long-term virologic failure [abstract LB10]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

Dybul M, Yoder C, Belson M, Chun T-W, Hallahan C, Justement JS, et al. A randomized, controlled trial of intermittent versus continuous highly-active antiretroviral therapy (HAART) [abstract LbOrIl]. Presented at the XIII International Conference on AIDS. Durban, South Africa, July 9–14, 2000.

Dybul M, Yoder C, Belson M, Hallahan C, Hertogs K, Larder B, et al. Short cycle intermittent HAART: a pilot study [abstract LbOr12]. Presented at the XIII International Conference on AIDS. Durban, South Africa, July 9–14, 2000.

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Garcia F, Plana M, Ortiz GM, Soriano A, Vidal C, Cruceta A, et al. Structured cyclic antiretroviral therapy interruption (STI) in chronic infection may induce immune responses against HIV-1 antigen associated with spontaneous drop in viral load [abstract LB11]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

• Geijtenbeek T.B.
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Harrigan PR, Whaley M, Dong W, Sherlock C, Hogg R, Teeple A, et al. No detectable HIV RNA in thirteen individuals months after stopping antiretroviral therapy [abstract 351]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

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Hatano H, Vogel S, Metcalf J, Yoder C, Deward R, Davey R, et al. Plasma viral loads approximate pre-HAART levels after discontinuation of HAART [abstract 349]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

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• Hauber J.

Havlir D, Hirsch MS, Richman DD, Bassett RL, Gilbert P, Tebas P, et al. Prevalence and predictive value of intermittent viremia in patients with viral suppression [abstract TuPeB3195]. Presented at the XIII International Conference on AIDS. Durban, South Africa, July 9–14, 2000.

Hege K, Wagnert B, Mitsuyasu R, Anto P, Scaddens D, Kwok S, et al. HIV-1 specific T-cell gene therapy suppresses viral load rebound in subjects on highly active antiretroviral therapy (HAART). Presented at the American Society of Gene Therapy Meeting. Denver, May 30, 2000.

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Hirscgel B, Fagad C, Lebraz M, Tortajada C, Garcia F, Bernasconi E, et al. The Swiss-Spanish intermittent trial (SSITT) [abstract ThOrB747]. Presented at the XIII International Conference on AIDS. Durban, South Africa, July 9–14, 2000.

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Kilby JM, Saag MS, Goeppert PA, Hockett RD, Saha BK, Bucy RP. Significant delay in plasma vRNA rebound during a scheduled treatment interruption in HIV-1 chronically infected patients previously on effective therapy [abstract 359]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

Lafeuillade A, Poggi C, Chollet L, Beauvais L, Van PN, Dohin E, et al. Aggressive HAART + IL-2 is unable to induce HIV remission in early-stage disease after 18 months [abstract 544]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

Lonnidis JPA, Havlir DV, Tebas P, Hirsch MS, Collier AC, Richman DD. Dynamics of HIV-1 viral load rebound among patients with previous suppression of viral replication [abstract 360]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

Lori F. Success of structured treatment interruptions (STI) in chronically infected patients depends on the antiretroviral regimen [abstract WePeB4289]. Presented at the XIII International Conference on AIDS. Durban, South Africa, July 9–14, 2000.

Lori F, Foli A, Maserati R, Seminari E, Minolf L, Alberici F, et al. Control of viremia after treatment interruption [abstract 352]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

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Orenstein JM, Bhat N, Yoder C, Fox C, Polis M, Metcalf J, et al. Rapid activation of lymph nodes upon interrupting HAART in HIV-infected patients following prolonged viral suppression [abstract 358]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

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Stellbrink HJ, Van Lunzen J, Westby M, O'Sullivan E, Cammack N, Adam A, et al. Influence of interleukin-2 (IL-2) on productive and latent HIV-1 infection and on viral rebound [abstract 240]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

Taoufik Y, Lambotte O, Wallon C, deGoer MG, Charles A, Delfraissy JR. In vitro, recombinant interleukin-2 and HIV-specific antigens activate HIV latently infected lymphocytes from patients on prolonged HAART [abstract 378]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

Tremblay C, Rosenberg E, Giguel F, Pppn S, Wong JT, Walker BD, et al. Stable peripheral blood HIV-1 reservoirs following structured therapy interruptions (STI) in two subjects [abstract #WePeB4287]. Presented at the XIII International Conference on AIDS. Durban, South Africa, July 9–14, 2000.

• Vila J.
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Wellons M, Jacobson AJ, Van Loon K, Miralles GD, Montefiori D, Bartlett JA, et al. A controlled trial of treatment interruption in chronically HIV-infected subjects [abstract WePeB4208]. Presented at the XIII International Conference on AIDS. Durban, South Africa, July 9–14, 2000.

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Wong J, Billingsley J, Wang Z, Liu Z, Qiu L, Kalams S, et al. Induction and elimination of latent HIV via T-cell activation [abstract 547]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.

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Zala C, Salomon H, Gun A, Raboud J, Pampuro S, Perez H, et al. Viral load rebound upon discontinuation of d4T + ddl and NVP with or without hydroxyurea (HU) during primary HIV infection (PHI) [abstract 558]. Presented at the 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, January 30–February 2, 2000.